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与保守治疗相比,小儿首次髌骨脱位的手术治疗可能会降低再脱位率:一项系统评价和荟萃分析。

Surgical management of first-time patellar dislocations in paediatric patients may lower rates of redislocation compared to conservative management: A systematic review and meta-analysis.

作者信息

Blackman Benjamin, Dworsky-Fried Joshua, Cohen Dan, Slawaska-Eng David, Gyemi Lauren, Simunovic Nicole, Peterson Devin, Ayeni Olufemi R, de Sa Darren

机构信息

School of Medicine, University of Limerick, Limerick, Ireland.

Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2025 Jun;33(6):2156-2166. doi: 10.1002/ksa.12524. Epub 2024 Oct 30.

Abstract

PURPOSE

The purpose of this study is to assess whether early surgical intervention for first-time patellar dislocations in paediatric patients is superior to conservative management. We hypothesized that surgical intervention would lead to lower redislocation rates compared to conservative treatment.

METHODS

Three online databases (PubMed, MEDLINE and EMBASE) were searched from inception to 14 March 2024 to identify studies investigating the management options for acute first-time patellar dislocations in paediatric patients. Data pertaining to patient demographics, patient management, redislocation rates and Kujala scores, evaluating function, were abstracted. Weighted means and meta-analyses were conducted to compare rates of redislocation, as well as Kujala scores. The quality of included studies was assessed using the methodological index for non-randomized studies criteria for non-randomized studies and the ROB2 tool for randomized controlled trials (RCTs).

RESULTS

A total of 11 studies and 761 patients were included in this review. The weighted mean post-operative combined rates of redislocation in the surgical group was 25.1%, compared to 46.4% in the conservative group at a mean follow-up of 53.2 months (12-168). The relative risk (RR) of redislocation was 0.82 (95% confidence interval [CI]: 0.65-1.04, I = 0%, p = 0.11), favouring surgery compared to conservative management. A subgroup meta-analysis of two recent RCTs with 110 patients demonstrated an RR of redislocation of 0.53 (95% CI: 0.31-0.91, I = 0%, p = 0.02), favouring surgery. Kujala scores among three comparative studies showed a mean difference of -2.7 (95% CI: -6.1 to 0.68, I = 0%, p = 0.12), favouring conservative treatment. The weighted mean redislocation rate in 131 patients undergoing medial patellofemoral ligament reconstruction (MPFLR) was 3.1%, compared to 39.4% in 203 patients undergoing other surgical procedures, such as lateral release and medial imbrication, Roux-Goldwaith and MPFL repair. Furthermore, the conservative groups experienced a complication rate of 0.9% compared to 2.9% across the surgical groups.

CONCLUSION

Surgical management for first-time patellar dislocations in a paediatric population, particularly MPFLR, may be more beneficial in lowering redislocation rates than conservative management. No significant differences in Kujala scores were found.

LEVEL OF EVIDENCE

Level IV.

摘要

目的

本研究旨在评估小儿首次髌骨脱位的早期手术干预是否优于保守治疗。我们假设与保守治疗相比,手术干预可降低再脱位率。

方法

检索了三个在线数据库(PubMed、MEDLINE和EMBASE),检索时间从建库至2024年3月14日,以确定关于小儿急性首次髌骨脱位治疗方案的研究。提取了与患者人口统计学、患者治疗、再脱位率和评估功能的库贾拉评分相关的数据。进行加权均值和荟萃分析以比较再脱位率以及库贾拉评分。使用非随机研究的方法学指标和随机对照试验(RCT)的ROB2工具评估纳入研究的质量。

结果

本综述共纳入11项研究和761例患者。手术组术后再脱位加权平均合并率为25.1%,而保守组在平均随访53.2个月(12 - 168个月)时为46.4%。再脱位的相对风险(RR)为0.82(95%置信区间[CI]:0.65 - 1.04,I² = 0%,p = 0.11),与保守治疗相比,手术更具优势。对两项近期有110例患者的RCT进行的亚组荟萃分析显示,再脱位的RR为0.53(95% CI:0.31 - 0.91,I² = 0%,p = 0.02),支持手术治疗。三项比较研究中的库贾拉评分显示平均差异为 - 2.7(95% CI: - 6.1至0.68,I² = 0%,p = 0.12),支持保守治疗。131例行内侧髌股韧带重建(MPFLR)患者的加权平均再脱位率为3.1%,而203例行其他手术(如外侧松解和内侧叠瓦成形术、Roux - Goldwaith术和MPFL修复)患者的再脱位率为39.4%。此外,保守组的并发症发生率为0.9%,而手术组为2.9%。

结论

小儿首次髌骨脱位的手术治疗,尤其是MPFLR,在降低再脱位率方面可能比保守治疗更有益。未发现库贾拉评分有显著差异。

证据级别

四级。

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