Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts, USA.
Department of Psychiatry and Behavioral Neuroscience, Morsani School of Medicine Tampa, University of South Florida, Tampa, Florida, USA.
Int J Methods Psychiatr Res. 2024 Dec;33(4):e70006. doi: 10.1002/mpr.70006.
To develop a composite score for differential resilience to effects of combat-related stressors (CRS) on persistent DSM-IV post-traumatic stress disorder (PTSD) among US Army combat arms soldiers using survey data collected before deployment.
A sample of n = 2542 US Army combat arms soldiers completed a survey shortly before deployment to Afghanistan and then again two to three and 8-9 months after redeployment. Retrospective self-reports were obtained about CRS. Precision treatment methods were used to determine whether differential resilience to persistent PTSD in the follow-up surveys could be developed from pre-deployment survey data in a 60% training sample and validated in a 40% test sample.
40.8% of respondents experienced high CRS and 5.4% developed persistent PTSD. Significant test sample heterogeneity was found in resilience (t = 2.1, p = 0.032), with average treatment effect (ATE) of high CRS in the 20% least resilient soldiers of 17.1% (SE = 5.5%) compared to ATE = 3.8% (SE = 1.2%) in the remaining 80%. The most important predictors involved recent and lifetime pre-deployment distress disorders.
A reliable pre-deployment resilience score can be constructed to predict variation in the effects of high CRS on persistent PTSD among combat arms soldiers. Such a score could be used to target preventive interventions to reduce PTSD or other resilience-related outcomes.
利用部署前收集的调查数据,为美国陆军作战部队士兵开发一种针对与战斗相关应激源(CRS)对持续性 DSM-IV 创伤后应激障碍(PTSD)影响的差异化弹性综合评分。
样本量为 n=2542 名美国陆军作战部队士兵,在部署到阿富汗前完成一项调查,然后在重新部署后 2-3 个月和 8-9 个月再次进行调查。通过回顾性自我报告获得关于 CRS 的信息。使用精准治疗方法来确定是否可以从部署前调查数据中开发出一种对后续调查中持续性 PTSD 的差异化弹性预测方法,然后在 60%的训练样本中进行验证,在 40%的测试样本中进行验证。
40.8%的受访者经历了高强度 CRS,5.4%的人发展为持续性 PTSD。在弹性方面,测试样本存在显著的异质性(t=2.1,p=0.032),在 20%最不具弹性的士兵中,高强度 CRS 的平均治疗效果(ATE)为 17.1%(SE=5.5%),而在其余 80%的士兵中,ATE 为 3.8%(SE=1.2%)。最重要的预测因素涉及近期和终身部署前的困扰障碍。
可以构建一个可靠的部署前弹性评分,以预测高强度 CRS 对作战部队士兵持续性 PTSD 影响的变化。这种评分可以用于针对预防干预措施,以减少 PTSD 或其他与弹性相关的结果。