MacDonald K J, Marks J
Br J Dermatol. 1986 Feb;114(2):235-9. doi: 10.1111/j.1365-2133.1986.tb02803.x.
Eighteen patients with chronic plaque psoriasis were investigated in two groups to determine the optimal contact time for the application of 2% anthralin, within the range immediate removal to removal at 20 min. It was found that clinical efficacy, assessed by times to plaque clearing, and side effects of treatment, i.e. erythema and staining, were independent of anthralin contact time. There seemed to be a relationship between erythema induction and skin type.
18名慢性斑块状银屑病患者被分为两组进行研究，以确定在即时清除至20分钟清除的范围内，2%地蒽酚的最佳涂抹接触时间。结果发现，通过斑块清除时间评估的临床疗效以及治疗的副作用，即红斑和染色，与地蒽酚接触时间无关。红斑诱发与皮肤类型之间似乎存在关联。
