Department of Oral and Maxillofacial Surgery, Hannover Medical School, Carl-Neuberg-Str. 1, 30625, Hannover, Germany.
Private Practice for Oral and Maxillofacial Surgery, Plastic Facial Surgery and Implantology, Theaterstr. 61, 52062, Aachen, Germany.
Clin Oral Investig. 2024 Oct 30;28(11):616. doi: 10.1007/s00784-024-06007-4.
This study analyzed complication rates of guided bone regeneration (GBR) using titanium-reinforced polytetrafluoroethylene (PTFE) membranes for alveolar ridge augmentation.
84 patients treated with GBR using titanium-reinforced PTFE membranes (91 sites) were retrospectively analyzed. Complications such as membrane exposure and early removal were analyzed concerning patient age, defect site position, size, simultaneous vs. two-stage implant placement, smoking, and the use of bone grafts (BG) and substitutes (BS).
Early removal due to membrane exposure was necessary in 14/91 sites (15.4%). No correlation was found between early removal and patient age (p = 0.917). Analyzing early removal between the upper and lower jaw and between both jaws' anterior and posterior tooth regions revealed no correlations (p = 0.381 and 0.477, respectively). Defect sites sizes of 5-6 mm exhibited the highest rate of membrane exposure, requiring early removal, accounting for 57.1% of these sites (8/14). No correlation was observed between the defect sites size and early removal (p = 0.660). Comparison of simultaneous (74 sites) vs. two-stage implant placement (16 sites) showed no correlation with early removal (p = 0.706). Membrane exposure incidence was 42.9% among smokers (27 patients, 32.1%) and 57.1% among non-smokers (57 patients, 67.9%), without correlation. No correlation was found between the type of BG and BS and early removal (p = 0.500).
GBR using titanium-reinforced PTFE membranes is effective for alveolar ridge augmentation and has favorable long-term outcomes.
Careful surgical technique and postoperative care can minimize the notable risk of PTFE membrane exposure.
本研究分析了使用钛增强聚四氟乙烯（PTFE）膜进行牙槽嵴增高的引导骨再生（GBR）的并发症发生率。
回顾性分析了 84 例接受钛增强 PTFE 膜（91 个部位）GBR 治疗的患者。分析了膜暴露和早期去除等并发症与患者年龄、缺损部位位置、大小、同期与二期种植体放置、吸烟以及使用骨移植物（BG）和替代品（BS）之间的关系。
14/91 个部位（15.4%）因膜暴露而需要早期去除。早期去除与患者年龄之间无相关性（p=0.917）。分析上下颌及前牙区和后牙区的早期去除，无相关性（p=0.381 和 0.477）。5-6mm 的缺损部位大小显示出最高的膜暴露率，需要早期去除，占这些部位的 57.1%（8/14）。缺损部位大小与早期去除之间无相关性（p=0.660）。同期（74 个部位）与二期种植体放置（16 个部位）的比较与早期去除无相关性（p=0.706）。吸烟者的膜暴露发生率为 42.9%（27 例，32.1%），非吸烟者为 57.1%（57 例，67.9%），无相关性。BG 和 BS 的类型与早期去除无相关性（p=0.500）。
使用钛增强 PTFE 膜的 GBR 是牙槽嵴增高的有效方法，具有良好的长期效果。
仔细的手术技术和术后护理可以最大程度地降低 PTFE 膜暴露的显著风险。
