四因子凝血酶原复合物浓缩剂在成人创伤出血管理中的应用
Four-factor Prothrombin Complex Concentrate Use for Bleeding Management in Adult Trauma.
作者信息
Mora Lidia, Maegele Marc, Grottke Oliver, Koster Andreas, Stein Philipp, Levy Jerrold H, Erdoes Gabor
机构信息
Department of Anesthesiology, Intensive Care and Pain Clinic, Vall d'Hebron Trauma, Rehabilitation and Burns Hospital, Autonomous University of Barcelona, Barcelona, Spain.
Department for Trauma and Orthopedic Surgery, Cologne-Merheim Medical Center, Witten/Herdecke University, Campus Cologne-Merheim, Cologne, Germany.
出版信息
Anesthesiology. 2025 Feb 1;142(2):351-363. doi: 10.1097/ALN.0000000000005230. Epub 2024 Oct 30.
The clinical use of four-factor prothrombin complex concentrate in adult trauma patients at risk of bleeding is supported by evidence for urgent reversal of oral anticoagulants but is controversial in acquired traumatic coagulopathy.
四因子凝血酶原复合物浓缩剂在有出血风险的成年创伤患者中的临床应用，有口服抗凝剂紧急逆转的证据支持，但在获得性创伤性凝血病中存在争议。
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