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本文引用的文献

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Functional and Symptomatic Clinical Trial Endpoints: The HFC-ARC Scientific Expert Panel.功能性和症状性临床终点：HFC-ARC 科学专家小组。
JACC Heart Fail. 2022 Dec;10(12):889-901. doi: 10.1016/j.jchf.2022.09.012. Epub 2022 Nov 9.
2
Impact of Patient-Reported Outcome Measurement in Heart Failure Clinic on Clinician Health Status Assessment and Patient Experience: A Substudy of the PRO-HF Trial.心力衰竭门诊中患者报告结局测量对临床医生健康状况评估和患者体验的影响：PRO-HF 试验的子研究。
Circ Heart Fail. 2023 Feb;16(2):e010280. doi: 10.1161/CIRCHEARTFAILURE.122.010280. Epub 2022 Nov 5.
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2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2022年美国心脏协会/美国心脏病学会/美国心力衰竭学会心力衰竭管理指南：美国心脏病学会/美国心脏协会临床实践指南联合委员会报告
Circulation. 2022 May 3;145(18):e895-e1032. doi: 10.1161/CIR.0000000000001063. Epub 2022 Apr 1.
4
Development and Initial Validation of the PROMIS®-Plus-HF Profile Measure.开发并初步验证 PROMIS®-Plus-HF 概况量表。
Circ Heart Fail. 2019 Jun;12(6):e005751. doi: 10.1161/CIRCHEARTFAILURE.118.005751. Epub 2019 Jun 5.
5
Utility of Patient-Reported Outcome Instruments in Heart Failure.患者报告结局量表在心力衰竭中的应用。
JACC Heart Fail. 2016 Mar;4(3):165-75. doi: 10.1016/j.jchf.2015.10.015. Epub 2016 Feb 10.

患者报告结局指标的兴起：心力衰竭临床试验的趋势

The Rise of Patient-Reported Outcome Measures: Trends in Heart Failure Clinical Trials.

作者信息

Khan Mirza S, Jawad Mohammad Abdel, Ikemura Nobuhiro, Sherrod Charles F, O'Keefe Evan L, Chan Paul S, Spertus John A, Fendler Timothy J

机构信息

Healthcare Institute for Innovations in Quality, University of Missouri-Kansas City, Kansas City, MO, USA; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.

Healthcare Institute for Innovations in Quality, University of Missouri-Kansas City, Kansas City, MO, USA; Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.

出版信息

J Card Fail. 2025 Apr;31(4):730-734. doi: 10.1016/j.cardfail.2024.09.019. Epub 2024 Oct 28.

DOI:10.1016/j.cardfail.2024.09.019
PMID:39477204
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11985288/
Abstract

Heart failure is a serious condition that affects millions of individuals worldwide. To make sure new treatments are safe and effective for use in patients, researchers conduct clinical trials. Traditionally, trials have examined how well treatments worked by studying how it affected outcomes like death and hospitalization rates, but they didn’t always ask the patients how they themselves were feeling. Our research shows that this is changing - more and more clinical trials are asking patients directly about their health status, e.g., symptoms, physical function, and quality of life.

摘要

心力衰竭是一种严重的疾病，影响着全球数百万人。为确保新疗法对患者使用时安全有效，研究人员会进行临床试验。传统上，试验通过研究疗法如何影响死亡和住院率等结果来考察其效果，但并不总是询问患者自身的感受。我们的研究表明这种情况正在改变——越来越多的临床试验直接询问患者的健康状况，例如症状、身体功能和生活质量。