School of Nursing and Midwifery, Department of Midwifery, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia
School of Nursing and Midwifery, Department of Midwifery, College of Medicine and Health Science, Wollo University, Dessie, Ethiopia.
BMJ Open. 2024 Oct 29;14(10):e083397. doi: 10.1136/bmjopen-2023-083397.
To assess the knowledge and acceptability of the human papillomavirus (HPV) vaccine and the associated factors among adolescent girls in public primary schools in Dessie Town, South Wollo, Northeast Ethiopia in 2020.
DESIGN, PARTICIPANTS AND METHODS: This was an institutional cross-sectional study conducted from 1 November to 30 November 2020 among 844 adolescent girls. A systematic random sampling method was used to select participants, who completed a pretested, self-administered questionnaire. Data were entered into EpiData V.4.6 and exported to SPSS V.25 for analysis. A binary logistic regression model identified the contributing factors to HPV vaccine knowledge and acceptance. Adjusted OR (AOR) and 95% CI computed at p<0.05 were used to assess significance levels.
The primary outcomes of interest were knowledge and acceptability of the HPV vaccine.
The HPV vaccine is known and acceptable to 47% and approximately 43% of the respondents, respectively. Age (AOR=3.51, 95% CI 1.62 to 7.6), father's educational level (AOR=2.62, 95% CI 1.57 to 4.38) and parent-child communication about sex and reproductive health (AOR=1.94, 95% CI 1.36 to 2.76) were associated with knowledge of the HPV vaccine. Acceptance of the HPV vaccine was significantly influenced by fathers' educational level (AOR=1.88, 95% CI:1.02 to 3.29), knowledge of Pap smear tests (AOR=2.54, 95% CI 1.79 to 3.62) and knowledge of the HPV vaccine (AOR=5.30, 95% CI 3.77 to 7.73).
In this study, there was generally good and high acceptance of the HPV vaccine, respectively, compared with a study conducted in Southwest Ethiopia. The study, however, had limitations in terms of recall bias, assessment of coverage/effectiveness over time and generalisability due to the institutional sample used.
评估 2020 年埃塞俄比亚南沃洛省德西镇公立小学青少年女孩对人乳头瘤病毒（HPV）疫苗的知识和可接受性及其相关因素。
设计、参与者和方法：这是一项于 2020 年 11 月 1 日至 30 日在 844 名青少年女孩中进行的机构横断面研究。采用系统随机抽样方法选择参与者，他们完成了一份预先测试的、自我管理的问卷。数据输入 EpiData V.4.6 并导出到 SPSS V.25 进行分析。二元逻辑回归模型确定了 HPV 疫苗知识和接受度的促成因素。使用调整后的 OR（AOR）和 p<0.05 的 95%CI 来评估显著性水平。
主要结果是 HPV 疫苗的知识和可接受性。
HPV 疫苗的知晓率和可接受率分别为 47%和 43%左右。年龄（AOR=3.51，95%CI 1.62 至 7.6）、父亲的教育水平（AOR=2.62，95%CI 1.57 至 4.38）和父母与孩子关于性和生殖健康的沟通（AOR=1.94，95%CI 1.36 至 2.76）与 HPV 疫苗知识相关。HPV 疫苗的接受率受到父亲教育水平（AOR=1.88，95%CI：1.02 至 3.29）、巴氏涂片检查知识（AOR=2.54，95%CI 1.79 至 3.62）和 HPV 疫苗知识（AOR=5.30，95%CI 3.77 至 7.73）的显著影响。
与在埃塞俄比亚西南部进行的研究相比，本研究中 HPV 疫苗的总体接受率较高。然而，由于使用了机构样本，该研究存在回忆偏倚、随着时间的推移评估覆盖率/有效性以及推广性方面的限制。
