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蜱传埃立克体病相关重度脓毒症并肺动脉高压:徒步前你应该知道的事。

Pulmonary hypertension with severe sepsis in ehrlichiosis: what you should know before you hike.

机构信息

Department of Medicine, Monmouth Medical Center, Long Branch, New Jersey, USA

Department of Medicine, Monmouth Medical Center, Long Branch, New Jersey, USA.

出版信息

BMJ Case Rep. 2024 Oct 30;17(10):e260202. doi: 10.1136/bcr-2024-260202.

DOI:10.1136/bcr-2024-260202
Abstract

Ehrlichiosis is a tickborne illness that can lead to an increased risk of death without appropriate treatment. According to Centers for Disease Control and Prevention, there has been a rise in incidence. We present a case of an immunocompetent patient who reported tick removal after hiking. Chest imaging showed pulmonary vascular congestion, extensive bilateral airspace and bibasilar moderate-dependent pleural effusions. Transthoracic echocardiography showed moderate pulmonary hypertension with right ventricular systolic pressure of 56.3 mm Hg. PCR testing came back positive. Doxycycline was started in the emergency department and continued for 14 days. The patient had a resolution of the pulmonary hypertension and decrease in tricuspid regurgitation. However, mild mitral regurgitation was persistent. The pulmonary hypertension may be caused by the patient's response to ehrlichiosis infection, but it may also be explained by the development of acute respiratory distress syndrome, which has been documented in multiple studies.

摘要

埃立克体病是一种蜱传疾病,如果不进行适当治疗,可能会导致死亡风险增加。根据疾病控制和预防中心的数据,该病的发病率有所上升。我们报告了一例免疫功能正常的患者,他在徒步旅行后报告了蜱虫去除情况。胸部影像学显示肺血管充血、广泛的双侧气腔和双基底中度依赖性胸腔积液。经胸超声心动图显示中度肺动脉高压,右心室收缩压为 56.3 毫米汞柱。PCR 检测结果为阳性。在急诊科开始使用多西环素治疗,持续 14 天。患者的肺动脉高压和三尖瓣反流减少得到缓解。然而,轻度二尖瓣反流仍然存在。肺动脉高压可能是由于患者对埃立克体感染的反应引起的,但也可能是由急性呼吸窘迫综合征引起的,这在多项研究中已有记载。

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本文引用的文献

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Ehrlichiosis presenting as severe sepsis and meningoencephalitis in an immunocompetent adult.埃立克体病在一名免疫功能正常的成年人中表现为严重脓毒症和脑膜脑炎。
JMM Case Rep. 2018 Jul 27;5(9):e005162. doi: 10.1099/jmmcr.0.005162. eCollection 2018 Sep.
2
Interstitial pneumonia and pulmonary hypertension associated with suspected ehrlichiosis in a dog.一只犬疑似埃立克体病伴发间质性肺炎和肺动脉高压。
Acta Vet Scand. 2016 Jul 7;58(1):46. doi: 10.1186/s13028-016-0228-1.
3
Diagnosis and Management of Tickborne Rickettsial Diseases: Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis - United States.
蜱传斑疹伤寒立克次体病的诊断和治疗:落矶山斑点热和其他斑点热群立克次体病、埃立克体病和无形体病 - 美国。
MMWR Recomm Rep. 2016 May 13;65(2):1-44. doi: 10.15585/mmwr.rr6502a1.
4
Increasing Incidence of Ehrlichiosis in the United States: A Summary of National Surveillance of Ehrlichia chaffeensis and Ehrlichia ewingii Infections in the United States, 2008-2012.美国埃立克体病发病率上升:2008 - 2012年美国恰菲埃立克体和尤因埃立克体感染国家监测总结
Am J Trop Med Hyg. 2016 Jan;94(1):52-60. doi: 10.4269/ajtmh.15-0540. Epub 2015 Nov 30.
5
Pulmonary hypertension associated with Ehrlichia canis infection in a dog.犬埃立克体感染相关的肺动脉高压
Vet Rec. 2012 Jun 30;170(26):676. doi: 10.1136/vr.100436. Epub 2012 May 29.
6
Human ehrlichiosis and anaplasmosis.人埃立克体病和无形体病。
Clin Lab Med. 2010 Mar;30(1):261-92. doi: 10.1016/j.cll.2009.10.004.
7
The importance of early treatment with doxycycline in human ehrlichiosis.强力霉素早期治疗在人类埃立克体病中的重要性。
Medicine (Baltimore). 2008 Mar;87(2):53-60. doi: 10.1097/MD.0b013e318168da1d.
8
Ehrlichia chaffeensis: a prevalent, life-threatening, emerging pathogen.查菲埃立克体:一种普遍存在、危及生命的新出现病原体。
Trans Am Clin Climatol Assoc. 2004;115:375-82; discussion 382-4.
9
Diagnosis and management of tickborne rickettsial diseases: Rocky Mountain spotted fever, ehrlichioses, and anaplasmosis--United States: a practical guide for physicians and other health-care and public health professionals.蜱传立克次体病的诊断与管理:落基山斑疹热、埃立克体病和无形体病——美国:面向医生及其他医疗保健和公共卫生专业人员的实用指南
MMWR Recomm Rep. 2006 Mar 31;55(RR-4):1-27.
10
Overproduction of TNF-alpha by CD8+ type 1 cells and down-regulation of IFN-gamma production by CD4+ Th1 cells contribute to toxic shock-like syndrome in an animal model of fatal monocytotropic ehrlichiosis.在致死性单核细胞增多性埃立克体病动物模型中,CD8 + 1型细胞过度产生肿瘤坏死因子-α以及CD4 + Th1细胞的γ干扰素产生下调,导致了中毒性休克样综合征。
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