Zhonghua Yu Fang Yi Xue Za Zhi. 2024 Dec 6;58(12):1807-1824. doi: 10.3760/cma.j.cn112150-20240802-00622.
The prevalence of food allergy in children is increasing, which seriously affects the quality of life of children and their families. Among children and adolescents, IgE-mediated food allergy is the most common type. In recent years, allergen specific IgE (sIgE) and skin prick testing (SPT) have been widely used in clinical practice, with component resolved diagnosis (CRD) also gaining traction for precise diagnosis of IgE-mediated food allergy. However, a challenge persists in clinical practice due to the tendency to over-interpret food allergen test results without considering the patient's clinical history. While food avoidance remains the most effective treatment for IgE-mediated food allergy, there are varying approaches to clinical management. Strict food avoidance for non-severe food allergies may increase the patient's burden and impact their quality of life. To address these challenges, a consensus on the diagnosis and management of IgE-mediated food allergy in children has been developed based on the latest guidelines and research evidence. This consensus aims to guide physicians in standardizing the management of IgE-mediated food allergy in children.
儿童食物过敏的患病率正在上升，这严重影响了儿童及其家庭的生活质量。在儿童和青少年中，IgE介导的食物过敏是最常见的类型。近年来，过敏原特异性IgE（sIgE）和皮肤点刺试验（SPT）已在临床实践中广泛应用，成分解析诊断（CRD）也因能精确诊断IgE介导的食物过敏而受到越来越多的关注。然而，由于在不考虑患者临床病史的情况下倾向于过度解读食物过敏原检测结果，临床实践中仍存在挑战。虽然避免食用相关食物仍然是IgE介导的食物过敏最有效的治疗方法，但临床管理方法各不相同。对于非严重食物过敏严格避免食用相关食物可能会增加患者负担并影响其生活质量。为应对这些挑战，基于最新指南和研究证据，已就儿童IgE介导的食物过敏的诊断和管理达成了共识。这一共识旨在指导医生规范儿童IgE介导的食物过敏的管理。
