Clinical Outcomes and Molecular Characteristics of Infections.

is the most common opportunistic anaerobic pathogen. In the absence of appropriate antimicrobial therapy, mortality rates associated with group infections can reach as high as 50%. Therefore, we aimed to elucidate the clinical characteristics and outcomes of infections and the molecular genetic characteristics of isolates. Forty clinical isolates were collected at Hanyang University Hospital between January 2022 and December 2023. Antimicrobial susceptibility was tested using the agar dilution method. Whole-genome sequencing was conducted using the Illumina platform (Illumina, San Diego, CA, USA). Various multilocus sequence types of were identified, including ST149 (N=4), ST11 (N=4), ST1 (N=3), ST21 (N=2), and ST157 (N=1). The insertion sequence (IS) IS, located upstream of , was associated with high-level carbapenem resistance in the ST157 isolate. toxin genes (bft ) were identified in 30% of isolates. The most common comorbidities were diabetes mellitus (26.5%) and non-metastatic cancer (23.5%). Five patients (14.7%) died within 30 days, and two (5.9%) deaths were directly attributable to infection. The emergence of high-level MIC carbapenem-resistant ST157 has led to caution in the presence of infections.