土耳其临床和肠道脆弱拟杆菌群分离株中肠毒素和抗生素抗性基因的流行情况。
The prevalence of enterotoxin and antibiotic resistance genes in clinical and intestinal Bacteroides fragilis group isolates in Turkey.
作者信息
Kangaba Achille Aime, Saglam Filiz Yarimcam, Tokman Hrisi Bahar, Torun Mert, Torun Muzeyyen Mamal
机构信息
Istanbul University, Cerrahpasa Medical Faculty, Department of Microbiology and Clinical Microbiology, Istanbul, Turkey.
Bahcesehir University, School of Medicine, Department of Medical Microbiology, Istanbul, Turkey.
出版信息
Anaerobe. 2015 Oct;35(Pt B):72-6. doi: 10.1016/j.anaerobe.2015.07.008. Epub 2015 Jul 26.
This study was conducted to measure the antibiotic susceptibilities, corresponding gene contents, and the enterotoxin gene bft, in 50 Bacteroides fragilis group isolates, 25 of which were clinical and 25 intestinal. The resistance rates to amoxicillin/clavulanic acid, imipenem and metronidazole were low; ampicillin and tetracyclin resistance was high; clindamycin resistance and ermF gene presence was also high. Regarding phenotypical bacterial resistance and the presence of resistance genes, there was not statistically significant difference between clinical and intestinal isolates and bft positive and negative isolates.
本研究旨在测定50株脆弱拟杆菌属分离株的抗生素敏感性、相应基因含量以及肠毒素基因bft，其中25株为临床分离株，25株为肠道分离株。对阿莫西林/克拉维酸、亚胺培南和甲硝唑的耐药率较低；对氨苄西林和四环素的耐药率较高；克林霉素耐药率和ermF基因携带率也较高。关于表型细菌耐药性和耐药基因的存在情况，临床分离株与肠道分离株之间以及bft阳性与阴性分离株之间无统计学显著差异。
Zotero 插件