Vallis M P, Cleeland J, Bradley P J, Morgan D A
Br J Radiol. 1986 Mar;59(699):251-6. doi: 10.1259/0007-1285-59-699-251.
A retrospective analysis of the results of treatment by primary irradiation of 87 cases of squamous-cell carcinoma of the tonsil at one institution over a 20-year period is presented. Survival at 5 years for all patients was 20%. The major determinants of survival were tumour size (T) and nodal status (N) at presentation. Degree of histological differentiation had no prognostic significance. Initial failure occurred in the primary tonsil site or in cervical lymph nodes in almost all cases. It is clear that treatments that increase loco-regional control are needed if the prognosis for the more advanced tumours is to be improved and it is suggested that a combined-modality approach (surgery plus irradiation) needs to be explored. For early lesions, primary radiation therapy remains the treatment of choice.
本文对某机构在20年期间对87例扁桃体鳞状细胞癌进行初次放疗的治疗结果进行了回顾性分析。所有患者的5年生存率为20%。生存的主要决定因素是就诊时的肿瘤大小（T）和淋巴结状态（N）。组织学分化程度无预后意义。几乎所有病例的初始失败都发生在原发扁桃体部位或颈部淋巴结。显然，如果要改善更晚期肿瘤的预后，就需要采取提高局部区域控制率的治疗方法，并且建议探索综合治疗方法（手术加放疗）。对于早期病变，原发性放射治疗仍然是首选治疗方法。
