Zhao Weijie, Shao Xinxin, Wang Ziyue, Mi Chuanhao, Wang Yu, Qi Xianghua, Ding Xiao
Department of First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, China.
Front Aging Neurosci. 2024 Oct 16;16:1413074. doi: 10.3389/fnagi.2024.1413074. eCollection 2024.
BACKGROUND: Deep Brain Stimulation (DBS) has been widely applied and accepted in the treatment of neurological and psychiatric disorders. Despite numerous studies exploring the effects of DBS on the progression of neurodegenerative diseases and the treatment of advanced Parkinson's disease (PD), there is a limited number of articles summarizing this research. The purpose of this study is to investigate the current trends, hot topics, and potential in research surrounding DBS therapy for PD, as well as to anticipate the challenges of such research. METHODS: We searched the Web of Science Core Collection database (WoSCC) for DBS research literature related to PD published from January 2014 to January 2024, utilized CiteSpace, VOS viewer, the bibliometric online analysis platform, Scimago Graphica, Microsoft Excel 2021, and R software version 4.2.3 for data analysis. And we conducted quantitative research on publications, citations, journals, authors, countries, institutions, keywords, and references, visualized the results in network graphs. RESULTS: From 2014 to 2024, papers from 39 journals from 11 countries were among the top 100 cited. Most papers were published in Neurology, with the highest average citations per paper in Nature Neuroscience. The United States (US) contributed the most publications, followed by the United Kingdom (UK) and Germany. In terms of total publications, University College London (UCL) contributed the most papers. The primary classifications of articles were Clinical Neurology, Neurosciences, and Surgery. The top five keywords were subthalamic nucleus, DBS, PD, medical therapy, and basal ganglia. Cluster analysis indicates that DBS research focus on improving quality of life and applying computational models. CONCLUSION: Through bibliometric analysis, researchers could quickly and clearly understand the hotspots and boundaries of their research field, thus guiding their research direction and scope to improve research efficiency and the quality of outcomes. Although studies indicate that DBS is currently a crucial method for treating advanced PD, in the long run, creating a personalized, low-cost treatment regimen with precise targeting and long-term efficacy poses a challenge.
背景:脑深部电刺激术(DBS)已在神经和精神疾病的治疗中得到广泛应用和认可。尽管有大量研究探讨了DBS对神经退行性疾病进展的影响以及对晚期帕金森病(PD)的治疗,但总结该研究的文章数量有限。本研究的目的是调查围绕DBS治疗PD的研究的当前趋势、热点话题和潜力,并预测此类研究的挑战。 方法:我们在科学网核心合集数据库(WoSCC)中搜索了2014年1月至2024年1月发表的与PD相关的DBS研究文献,利用CiteSpace、VOS viewer、文献计量在线分析平台、Scimago Graphica、Microsoft Excel 2021和R软件版本4.2.3进行数据分析。我们对出版物、引用、期刊、作者、国家、机构、关键词和参考文献进行了定量研究,并将结果以网络图的形式可视化。 结果:2014年至2024年期间,来自11个国家的39种期刊的论文被列入被引次数前100名。大多数论文发表在《神经病学》上,《自然神经科学》每篇论文的平均被引次数最高。美国的出版物数量最多,其次是英国和德国。就总出版物数量而言,伦敦大学学院(UCL)贡献的论文最多。文章的主要分类是临床神经病学、神经科学和外科学。前五个关键词是丘脑底核、DBS、PD、药物治疗和基底神经节。聚类分析表明,DBS研究侧重于提高生活质量和应用计算模型。 结论:通过文献计量分析,研究人员可以快速、清晰地了解其研究领域的热点和边界,从而指导其研究方向和范围,提高研究效率和成果质量。尽管研究表明DBS目前是治疗晚期PD的关键方法,但从长远来看,制定一种具有精确靶向性和长期疗效的个性化、低成本治疗方案仍面临挑战。
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