Gholami Zeinab, Paknahad Zamzam
School of Nutrition and Food Sciences, Students' Research Committee Isfahan University of Medical Sciences Isfahan Iran.
Department of Clinical Nutrition, School of Nutrition and Food Sciences Isfahan University of Medical Sciences Isfahan Iran.
Food Sci Nutr. 2024 Aug 29;12(10):7075-7087. doi: 10.1002/fsn3.3863. eCollection 2024 Oct.
Based on available evidence, psyllium has been found to play a role in preventing and improving hypertension. In light of this, the objective of this investigation is to perform a systematic review and meta-analysis to assess the effect of psyllium intake on blood pressure. In order to identify suitable publications, we conduct searches using Scopus, ISI Web of Science (WOS), and PubMed, and from 15 March 2022 to 15 July 2022. This study aims to evaluate the impact of psyllium consumption on blood pressure in adults through randomized controlled trials (RCTs). We used the fixed-effects model which are expressed as weighted mean differences (WMD) with 95% confidence intervals (CI). In this article, 14 RCT studies and 802 participants were included. Psyllium consumption significantly decreases systolic blood pressure (SBP): (weighted mean difference [WMD]: -2.24; 95% CI: -3.13, -1.35; < .05), and non-significantly increases diastolic blood pressure (DBP): (WMD: 0.04; 95% CI: -0.52, 0.61; > .05). Psyllium dosage and duration of consumption had a remarkable linear effect on SBP and DBP. Results showed a significant decrease in SBP and a non-significant increase in DBP following psyllium consumption.
基于现有证据，已发现车前草在预防和改善高血压方面发挥作用。有鉴于此，本调查的目的是进行系统评价和荟萃分析，以评估摄入车前草对血压的影响。为了确定合适的出版物，我们在2022年3月15日至2022年7月15日期间使用Scopus、ISI科学网（WOS）和PubMed进行检索。本研究旨在通过随机对照试验（RCT）评估成年人食用车前草对血压的影响。我们使用固定效应模型，以加权平均差（WMD）和95%置信区间（CI）表示。本文纳入了14项RCT研究和802名参与者。食用车前草可显著降低收缩压（SBP）：（加权平均差[WMD]：-2.24；95%CI：-3.13，-1.35；P<0.05），对舒张压（DBP）的升高无显著影响：（WMD：0.04；95%CI：-0.52，0.61；P>0.05）。车前草的剂量和食用持续时间对收缩压和舒张压有显著的线性影响。结果显示，食用车前草后收缩压显著降低，舒张压无显著升高。
