Coopersmith R, Lee S, Leon M
Brain Res. 1986 Jan;389(1-2):271-7. doi: 10.1016/0165-3806(86)90195-1.
The increased olfactory bulb response by young rats to familiar odors was not observed in response to odors which have attained their familiarity in aversive situations. Odor experience associated with toxicosis induced a behavioral aversion to the odor which was not accompanied by the enhanced uptake of [14C]2-deoxyglucose (2-DG) that accompanies attractive familiar odors. A single odor exposure on day 17 was sufficient to induce a small increase in 2-DG uptake in specific glomerular areas. We hypothesize that a different neural substrate underlies familiarity associated with an aversive odor than that associated with an attractive odor.
幼鼠对熟悉气味的嗅球反应增强，但在对在厌恶情境中变得熟悉的气味的反应中未观察到这种增强。与中毒相关的气味体验会引发对该气味的行为厌恶，且这种厌恶并未伴随有吸引力的熟悉气味所具有的[14C]2-脱氧葡萄糖（2-DG）摄取增加。在第17天单次接触气味足以使特定肾小球区域的2-DG摄取略有增加。我们推测，与厌恶气味相关的熟悉感所基于的神经基质与与有吸引力气味相关的神经基质不同。
