• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

清创时机:何时进行,应由谁来进行?

Timing of debridement: When to do it, and who should perform it?

机构信息

Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom.

Royal Infirmary of Edinburgh, Edinburgh, Scotland, United Kingdom.

出版信息

Injury. 2024 Nov;55 Suppl 6:111604. doi: 10.1016/j.injury.2024.111604.

DOI:10.1016/j.injury.2024.111604
PMID:39482022
Abstract

The timely and effective management of open fractures continues to be a challenge in modern orthopaedic practice. Lower limb high energy fractures with complex soft tissue injuries require multi-disciplinary care to achieve the best results. Despite an extensive published literature on open fractures, the timing of debridement and the most appropriate personnel to perform it continue to be a source of debate. National guidelines on the topic are few but they suggest immediate debridement for open fractures with highly contaminated wounds and debridement within 12 to 24 h is considered desirable for less contaminated wounds. There is actually limited evidence linking timing of debridement to infection risk but the largest studies recently published do indicate a link between delay to debridement and increasing infection risk. Most studies on management are based on a clinical model where the initial debridement and fixation are performed by an orthopaedic surgeon and if required delayed coverage and closure is subsequently carried out by a plastic surgeon. More recently, studies have proposed an alternative approach, with initial debridement and temporary fixation followed within 48 h with a further debridement, definitive fixation and flap cover with a combined orthoplastic team. Reported results have been favourable. This is a significant change in management and there are limited data at present to determine if this approach will improve results in the most complex open fractures.

摘要

在现代骨科实践中,及时有效地处理开放性骨折仍然是一个挑战。下肢高能骨折伴复杂软组织损伤需要多学科护理,以达到最佳效果。尽管有大量关于开放性骨折的文献,但清创的时机和最合适的人员进行清创仍然存在争议。关于这个主题的国家指南很少,但它们建议对高度污染的伤口立即进行清创,对污染较少的伤口,在 12 至 24 小时内进行清创是理想的。实际上,将清创时间与感染风险联系起来的证据有限,但最近发表的最大规模研究确实表明,清创时间延迟与感染风险增加之间存在关联。大多数关于管理的研究都是基于临床模型,即最初的清创和固定由骨科医生进行,如果需要,随后由整形外科医生进行延迟覆盖和闭合。最近,有研究提出了一种替代方法,即在最初的清创和临时固定后 48 小时内进行进一步的清创、确定性固定和皮瓣覆盖,由联合骨科和整形外科团队进行。报告的结果是有利的。这是管理上的重大变化,目前数据有限,无法确定这种方法是否会改善最复杂的开放性骨折的结果。

相似文献

1
Timing of debridement: When to do it, and who should perform it?清创时机:何时进行,应由谁来进行?
Injury. 2024 Nov;55 Suppl 6:111604. doi: 10.1016/j.injury.2024.111604.
2
Single-stage orthoplastic reconstruction of Gustilo-Anderson Grade III open tibial fractures greatly reduces infection rates.对 Gustilo-Anderson Ⅲ 型开放性胫骨骨折进行一期矫形重建可大幅降低感染率。
Injury. 2015 Nov;46(11):2263-6. doi: 10.1016/j.injury.2015.08.027. Epub 2015 Aug 22.
3
Institutional Experience and Orthoplastic Collaboration Associated with Improved Flap-based Limb Salvage Outcomes.机构经验和整形协作与改善基于皮瓣的肢体保肢结果相关。
Clin Orthop Relat Res. 2021 Nov 1;479(11):2388-2396. doi: 10.1097/CORR.0000000000001925.
4
Fix and flap: the radical orthopaedic and plastic treatment of severe open fractures of the tibia.固定与皮瓣:胫骨严重开放性骨折的根治性骨科与整形治疗
J Bone Joint Surg Br. 2000 Sep;82(7):959-66. doi: 10.1302/0301-620x.82b7.10482.
5
A comparison between the Major Trauma Centre management of complex open lower limb fractures in children and the elderly.儿童与老年复杂开放性下肢骨折患者在创伤中心的治疗比较。
Injury. 2019 Jul;50(7):1376-1381. doi: 10.1016/j.injury.2019.05.001. Epub 2019 May 2.
6
A representative assessment of the management of open fractures of the lower limb within UK orthoplastic centres: A two-centre audit of compliance with national standards.英国整形外科中心下肢开放性骨折治疗的代表性评估:一项关于符合国家标准情况的双中心审计
Injury. 2017 Oct;48(10):2266-2269. doi: 10.1016/j.injury.2017.07.012. Epub 2017 Jul 11.
7
Lower limb paediatric trauma with bone and soft tissue loss: Ortho-plastic management and outcome in a major trauma centre.下肢小儿创伤伴骨和软组织缺失:大型创伤中心的矫形处理和结果。
Injury. 2020 Jul;51(7):1576-1583. doi: 10.1016/j.injury.2020.03.059. Epub 2020 May 7.
8
The management of open tibial fractures in children: a retrospective case series of eight years' experience of 61 cases at a paediatric specialist centre.儿童开放性胫骨骨折的治疗:一家儿科专科中心八年61例病例的回顾性系列研究
Bone Joint J. 2017 Apr;99-B(4):544-553. doi: 10.1302/0301-620X.99B4.37855.
9
Delayed flap coverage of open extremity fractures after previous vacuum-assisted closure (VAC) therapy - worse or worth?先前采用负压封闭引流(VAC)治疗后开放性四肢骨折的延迟皮瓣覆盖——效果更差还是值得一试?
J Plast Reconstr Aesthet Surg. 2009 May;62(5):675-83. doi: 10.1016/j.bjps.2007.09.041. Epub 2008 Mar 25.
10
[Modern concepts of interdisciplinary extremity reconstruction in open fractures].[开放性骨折跨学科肢体重建的现代概念]
Unfallchirurgie (Heidelb). 2024 Jun;127(6):469-480. doi: 10.1007/s00113-024-01437-x. Epub 2024 May 13.

引用本文的文献

1
Early Flap Reconstruction and Infection Rates in Open Lower Extremity Fractures: A Systematic Review and Meta-analysis.开放性下肢骨折的早期皮瓣重建与感染率:系统评价与荟萃分析
Plast Reconstr Surg Glob Open. 2025 Jun 6;13(6):e6829. doi: 10.1097/GOX.0000000000006829. eCollection 2025 Jun.