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Evaluation of real-world efficacy of mepolizumab on SNOT-22 outcomes in patients with unified airway disease.

作者信息

González-Pérez Ruperto, Poza-Guedes Paloma, Martín-Voso María Gabriela, Sánchez-Machín Inmaculada

机构信息

Allergy Department, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain.

Severe Asthma Unit, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain.

出版信息

Clin Transl Allergy. 2024 Nov;14(11):e70006. doi: 10.1002/clt2.70006.

DOI:10.1002/clt2.70006
PMID:39482847
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11527812/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e171/11527812/e6bf0f58d5b1/CLT2-14-e70006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e171/11527812/e6bf0f58d5b1/CLT2-14-e70006-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e171/11527812/e6bf0f58d5b1/CLT2-14-e70006-g001.jpg

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本文引用的文献

1
Mepolizumab in Patients With Severe Asthma and Comorbidities: 1-Year REALITI-A Analysis.美泊利珠单抗治疗重度哮喘合并症患者：1年REALITI-A分析
J Allergy Clin Immunol Pract. 2023 Dec;11(12):3650-3661.e3. doi: 10.1016/j.jaip.2023.07.024. Epub 2023 Jul 26.
2
The Unified Airway Hypothesis: Evidence From Specific Intervention With Anti-IL-5 Biologic Therapy.统一气道假说：抗 IL-5 生物疗法的具体干预证据。
J Allergy Clin Immunol Pract. 2023 Sep;11(9):2630-2641. doi: 10.1016/j.jaip.2023.05.011. Epub 2023 May 18.
3
Mepolizumab improves quality of life and reduces activity impairments in patients with CRSwNP.
美泊利珠单抗可改善伴有鼻息肉的慢性鼻窦炎患者的生活质量并减少活动损伤。
Rhinology. 2022 Dec 1;60(6):474-478. doi: 10.4193/Rhin22.053.
4
Type 2 inflammation in asthma and other airway diseases.哮喘及其他气道疾病中的2型炎症
ERJ Open Res. 2022 Aug 1;8(3). doi: 10.1183/23120541.00576-2021. eCollection 2022 Jul.
5
European Position Paper on Rhinosinusitis and Nasal Polyps 2020.欧洲鼻窦炎和鼻息肉 2020 年立场文件。
Rhinology. 2020 Feb 20;58(Suppl S29):1-464. doi: 10.4193/Rhin20.600.
6
The 22-Item Sinonasal Outcome Test as a Tool for the Assessment of Quality of Life and Symptom Control in Allergic Rhinitis.22项鼻鼻窦结局测试作为评估变应性鼻炎患者生活质量和症状控制情况的工具。
Am J Rhinol Allergy. 2020 Mar;34(2):209-216. doi: 10.1177/1945892419884789. Epub 2019 Nov 4.
7
Next-generation Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines for allergic rhinitis based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) and real-world evidence.基于推荐评估、制定与评价（GRADE）分级和真实世界证据的新一代变应性鼻炎及其对哮喘（ARIA）指南：变应性鼻炎。
J Allergy Clin Immunol. 2020 Jan;145(1):70-80.e3. doi: 10.1016/j.jaci.2019.06.049. Epub 2019 Oct 15.
8
Minimal clinically important difference for the 22-item Sinonasal Outcome Test in medically managed patients with chronic rhinosinusitis.慢性鼻-鼻窦炎患者经药物治疗后 22 项鼻鼻窦结局测试的最小临床重要差异。
Clin Otolaryngol. 2018 Oct;43(5):1328-1334. doi: 10.1111/coa.13177. Epub 2018 Jul 26.