Espiridion Eduardo D, Murdock Andrew S, Guani Lorenzo E, Arshoun Angelica
Psychiatry, Drexel University College of Medicine, Philadelphia, USA.
Psychiatry, Reading Hospital, Tower Health, West Reading, USA.
Cureus. 2024 Oct 1;16(10):e70585. doi: 10.7759/cureus.70585. eCollection 2024 Oct.
Olanzapine is an antipsychotic medication that is used in the management of schizophrenia and bipolar disorder, but it is not without any adverse effects. We present the following case of a 24-year-old man with a history of schizoaffective disorder, obesity, and anxiety, who developed hypertriglyceridemia-induced acute pancreatitis after six months on olanzapine. Despite his adherence to the medication, routine metabolic monitoring was not performed leading to a delayed diagnosis of hypertriglyceridemia and subsequent complications. The case underscores the critical need for regular metabolic monitoring in patients prescribed olanzapine to prevent severe adverse effects and guide timely intervention. Enhanced adherence to monitoring guidelines and consideration of alternative treatments may help mitigate such risks.
奥氮平是一种抗精神病药物，用于治疗精神分裂症和双相情感障碍，但并非没有任何不良反应。我们报告以下病例：一名24岁男性，有分裂情感性障碍、肥胖和焦虑病史，在服用奥氮平六个月后发生高甘油三酯血症性急性胰腺炎。尽管他坚持服药，但未进行常规代谢监测，导致高甘油三酯血症诊断延迟及随后的并发症。该病例强调了对服用奥氮平的患者进行定期代谢监测的迫切需要，以预防严重不良反应并指导及时干预。加强对监测指南的遵守以及考虑替代治疗可能有助于降低此类风险。
