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不明原因的横纹肌溶解症和肝肾功能障碍：一例棒曲霉素中毒病例

Unexplained Rhabdomyolysis and Hepatic Renal Dysfunction: A Case of Bongkrekic Acid Poisoning.

作者信息

Hu RongMing, Fu TieGang, Xia SenLin, Fei ShuYing, Yin ZhuXiao

机构信息

Emergency Medicine, Huzhou Central Hospital, Huzhou, CHN.

Medicine, Hangzhou Dian Medical Laboratory Co. Ltd., Hangzhou, CHN.

出版信息

Cureus. 2024 Oct 1;16(10):e70625. doi: 10.7759/cureus.70625. eCollection 2024 Oct.

DOI:10.7759/cureus.70625
PMID:39483585
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11526843/
Abstract

Bongkrekic acid (BA) is a lipotoxin that can cause fatal food poisoning. Severe BA poisoning can rapidly progress from liver and kidney damage to multiple organ failure and is rarely manifested as persistent hypoglycemia and rhabdomyolysis. It has a high mortality rate and poor prognosis. However, clinical data on patients with foodborne BA poisoning are limited. The aim of this study is to summarize the characteristics of patients with BA poisoning, provide reference for early diagnosis and treatment, and improve the survival rate and prognosis of patients with BA poisoning.

摘要

邦克雷酸（BA）是一种可导致致命食物中毒的脂毒素。严重的BA中毒可迅速从肝肾功能损害发展为多器官功能衰竭，很少表现为持续性低血糖和横纹肌溶解。其死亡率高，预后差。然而，食源性BA中毒患者的临床资料有限。本研究的目的是总结BA中毒患者的特点，为早期诊断和治疗提供参考，提高BA中毒患者的生存率和预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/0e01714fe14c/cureus-0016-00000070625-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/466e145cc67d/cureus-0016-00000070625-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/e2ece5cfdd32/cureus-0016-00000070625-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/a13df85aed4b/cureus-0016-00000070625-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/957b6c4fd249/cureus-0016-00000070625-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/a2582f84efb0/cureus-0016-00000070625-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/198772a6799f/cureus-0016-00000070625-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/5083af4780c6/cureus-0016-00000070625-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/0e01714fe14c/cureus-0016-00000070625-i08.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/466e145cc67d/cureus-0016-00000070625-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/e2ece5cfdd32/cureus-0016-00000070625-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/a13df85aed4b/cureus-0016-00000070625-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/957b6c4fd249/cureus-0016-00000070625-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/a2582f84efb0/cureus-0016-00000070625-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/198772a6799f/cureus-0016-00000070625-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/5083af4780c6/cureus-0016-00000070625-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2565/11526843/0e01714fe14c/cureus-0016-00000070625-i08.jpg

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J Infect. 2024 Jul;89(1):106182. doi: 10.1016/j.jinf.2024.106182. Epub 2024 May 17.
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