Tefera Elias Manaye, Tefera Yibekal Manaye, Yimer Mekonnen, Mulat Worku Biruk, Ayele Eleni, Zewdu Asmare Bedilu, Abebe Gebrehana Deresse, Nega Godana Tilahun
Department of Internal Medicine, College of Medicine and Health Science, Wollo University, Wollo, Ethiopia.
Department of Public Health, Collage of Medicine and Health Science, Dire-Dawa University, Dire Dawa, Ethiopia.
Clin Med Insights Endocrinol Diabetes. 2024 Sep 30;17:11795514241285347. doi: 10.1177/11795514241285347. eCollection 2024.
The most prevalent heart symptom of hyperthyroidism is atrial fibrillation. Other than sinus tachycardia, which occurs with hyperthyroidism, atrial fibrillation is the most prevalent cardiac arrhythmia. Hyperthyroidism results in excess mortality from increased incidence of circulatory diseases and dysrhythmias. The aims of the study was prevalence and associated factors of atrial fibrillation among hyperthyroidism adult patients attending the University of Gondar Referral Hospital, Northwest Ethiopia.
This study aimed to determine the prevalence and associated factors of atrial fibrillation among adult hyperthyroid patients attending the University Of Gondar Referral Hospital, Ethiopia.
Using a consecutive sampling technique, 228 patients with hyperthyroidism participated in an institution-based cross-sectional study. A standardized questionnaire that had been pretested was used to gather the data that was designed to include socio-demographic data, clinical presentation, biochemical profile, and electrocardiography findings through chart review and interviews. The data were manually curated.
Atrial fibrillation was present in 32 (14%) patients, with a 95% CI of 9.6 to 19.2. The identified predictor variables were age >61 years (Adjusted Odd Ratio = 4.2, 95% CI = 1.5-11.7), female sex (Adjusted Odd Ratio = 4.0, 95% CI = 1.4-12.0), and high serum FT4 >23.9 pmol/l (Adjusted Odd Ratio = 8.0, 95% CI = 2.1-30.0).
The prevalence of atrial fibrillation among hyperthyroidism patients was 14%. Being female, being older, and having high serum FT4 levels were significantly associated with AF in hyperthyroid patients.
甲状腺功能亢进最常见的心脏症状是心房颤动。除甲状腺功能亢进时出现的窦性心动过速外，心房颤动是最常见的心律失常。甲状腺功能亢进会因循环系统疾病和心律失常发病率增加而导致死亡率上升。本研究的目的是调查埃塞俄比亚西北部贡德尔大学转诊医院成年甲状腺功能亢进患者中心房颤动的患病率及相关因素。
本研究旨在确定埃塞俄比亚贡德尔大学转诊医院成年甲状腺功能亢进患者心房颤动的患病率及相关因素。
采用连续抽样技术，228例甲状腺功能亢进患者参与了一项基于机构的横断面研究。通过图表回顾和访谈，使用经过预测试的标准化问卷收集数据，该问卷旨在纳入社会人口统计学数据、临床表现、生化指标和心电图检查结果。数据进行了人工整理。
32例（14%）患者存在心房颤动，95%置信区间为9.6至19.2。确定的预测变量为年龄>61岁（调整后比值比=4.2，95%置信区间=1.5-11.7）、女性（调整后比值比=4.0，95%置信区间=1.4-12.0）和血清游离甲状腺素>23.9 pmol/l（调整后比值比=8.0，95%置信区间=2.1-30.0）。
甲状腺功能亢进患者中心房颤动的患病率为14%。女性、年龄较大和血清游离甲状腺素水平较高与甲状腺功能亢进患者的心房颤动显著相关。
