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本文引用的文献

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Postoperative racial disparities following spine surgery are less pronounced in the outpatient setting.脊柱手术后门诊环境下的种族差异不那么明显。
Spine J. 2024 Aug;24(8):1361-1368. doi: 10.1016/j.spinee.2024.01.019. Epub 2024 Jan 30.
2
Interventional Therapy and Surgical Management of Lumbar Disc Herniation in Spine Surgery: A Narrative Review.脊柱外科中腰椎间盘突出症的介入治疗与手术管理:一项叙述性综述
Orthop Rev (Pavia). 2023 Nov 22;15:88931. doi: 10.52965/001c.88931. eCollection 2023.
3
Practical answers to frequently asked questions in minimally invasive lumbar spine surgery.微创腰椎手术常见问题的实用解答。
Spine J. 2023 Jan;23(1):54-63. doi: 10.1016/j.spinee.2022.07.087. Epub 2022 Jul 15.
4
Association between muscle health and patient-reported outcomes after lumbar microdiscectomy: early results.腰椎间盘切除术后肌肉健康与患者报告结果的关系:早期结果。
Spine J. 2022 Oct;22(10):1677-1686. doi: 10.1016/j.spinee.2022.05.013. Epub 2022 Jun 6.
5
Primary Versus Revision Discectomy for Adults With Herniated Nucleus Pulposus: A Propensity Score-Matched Multicenter Study.成人腰椎间盘突出症初次与翻修椎间盘切除术:一项倾向评分匹配的多中心研究
Global Spine J. 2018 Dec;8(8):810-815. doi: 10.1177/2192568218773716. Epub 2018 May 3.
6
Risk factors for recurrent lumbar disc herniation after discectomy.椎间盘切除术后腰椎间盘突出症复发的危险因素。
Int Orthop. 2019 Apr;43(4):963-967. doi: 10.1007/s00264-018-4201-7. Epub 2018 Oct 16.
7
Reoperation for Recurrent Intervertebral Disc Herniation in the Spine Patient Outcomes Research Trial: Analysis of Rate, Risk Factors, and Outcome.脊柱患者疗效研究试验中复发性椎间盘突出症的再次手术:发生率、危险因素及疗效分析
Spine (Phila Pa 1976). 2017 Jul 15;42(14):1106-1114. doi: 10.1097/BRS.0000000000002088.
8
Nationwide Databases in Orthopaedic Surgery Research.骨科手术研究中的全国性数据库。
J Am Acad Orthop Surg. 2016 Oct;24(10):673-82. doi: 10.5435/JAAOS-D-15-00217.
9
Risk Factors for Reoperation in Patients Treated Surgically for Intervertebral Disc Herniation: A Subanalysis of Eight-Year SPORT Data.接受椎间盘突出症手术治疗患者再次手术的危险因素:对八年的SPORT数据的亚分析
J Bone Joint Surg Am. 2015 Aug 19;97(16):1316-25. doi: 10.2106/JBJS.N.01287.
10
Risk factors for recurrent lumbar disc herniations.复发性腰椎间盘突出症的危险因素。
Asian Spine J. 2014 Apr;8(2):211-5. doi: 10.4184/asj.2014.8.2.211. Epub 2014 Apr 8.

初次与翻修椎间盘切除术术后并发症及结局的比较:一项全国性数据库分析。

Comparison of postoperative complications and outcomes following primary versus revision discectomy: A national database analysis.

作者信息

Hoang Ryan, Song Junho, Tiao Justin, Trent Sarah, Ngan Alex, Hoang Timothy, Kim Jun S, Cho Samuel K, Hecht Andrew C, Essig David, Virk Sohrab, Katz Austen D

机构信息

Department of Orthopaedic Surgery, School of Medicine, The University of California, Irvine, CA.

Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York.

出版信息

J Craniovertebr Junction Spine. 2024 Jul-Sep;15(3):303-307. doi: 10.4103/jcvjs.jcvjs_97_24. Epub 2024 Sep 12.

DOI:10.4103/jcvjs.jcvjs_97_24
PMID:39483833
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11524557/
Abstract

BACKGROUND

Lumbar microdiscectomy is a surgical procedure that is frequently used in the treatment of symptomatic lumbar herniation. Differences in outcomes following primary and revision lumbar microdiscectomy have been previously studied, with reports of comparably satisfactory results from the Spine Patient Outcomes Research Trial. In this study, we further investigate these outcomes, including length of stay, bleeding events, and durotomy. We hypothesized that length of stay, incidence of bleeding events, and dural tear would be greater in the revision cohort.

METHODS

The ACS-National Surgical Quality Improvement Program database was queried for patients undergoing single-level primary and revision lumbar microdiscectomy between 2019 and 2022. Eligibility for inclusion was determined by age >18 years and current procedural terminology codes 63030 and 63042. Patients with preoperative sepsis or cancer were excluded. Length of stay, wound infection, bleeding events requiring transfusion, cerebrospinal fluid leak, dural tear, and neurological injury were compared between the cohorts. Multivariable Poisson regression adjusted for demographics and comorbidities, including age, sex, race, body mass index, diabetes, smoking, and hypertension, was used to determine if revision was predictive of complications.

RESULTS

A total of 37,669 patients were included, of whom 3,635 (9.6%) required revision surgery. Patients in the revision cohort were older (54.25 ± 15.7 vs. 50.85 ± 16.0 years, < 0.001) and had higher proportions of male (59.0% vs. 55.7%, < 0.001) and non-Hispanic White patients (82.0% vs. 77.4%, < 0.001). Length of stay (1.11 ± 2.5 vs. 1.58 ± 2.7, < 0.001) and rates of wound infection (2.1% vs. 1.4%, = 0.002) and bleeding events requiring transfusion (1.3% vs. 0.7%, < 0.001) were greater in the revision cohort compared to primary patients. Differences in cerebrospinal fluid leak (0.2% vs. 0.1%, = 0.116), dural tear complication (0.01% vs. 0.01%, = 0.092), and neurological injury (0.008% vs. 0.006%, = 0.691) between the revision and primary cohorts were nonsignificant. Poisson log-linear regression adjusted for demographics and comorbidities demonstrated revision as a significant predictor for length of stay ( = 462.95, < 0.001), wound infection ( = 9.22, = 0.002), and bleeding events ( = 9.74, = 0.002), while it was a nonsignificant predictor of cerebrospinal fluid leak ( = 2.61, = 0.106), dural tear ( = 2.37, = 0.123), and neurological injury ( = 0.229, = 0.632).

CONCLUSION

Revision surgery was a significant predictor of increased length of stay, wound infection, and bleeding events requiring transfusion. Surgeons and patients alike should be aware of increased risk for complications following revision lumbar microdiscectomy compared to primary discectomy.

摘要

背景

腰椎显微椎间盘切除术是一种常用于治疗有症状的腰椎间盘突出症的外科手术。先前已经研究了初次和翻修腰椎显微椎间盘切除术后的结果差异,脊柱患者预后研究试验报告了结果同样令人满意。在本研究中,我们进一步调查这些结果,包括住院时间、出血事件和硬脊膜切开术。我们假设翻修组的住院时间、出血事件发生率和硬脊膜撕裂会更高。

方法

查询美国外科医师学会-国家外科质量改进计划数据库中2019年至2022年期间接受单节段初次和翻修腰椎显微椎间盘切除术的患者。纳入标准为年龄>18岁且当前程序术语编码为63030和63042。排除术前有败血症或癌症的患者。比较两组之间的住院时间、伤口感染、需要输血的出血事件、脑脊液漏、硬脊膜撕裂和神经损伤情况。使用多变量泊松回归对人口统计学和合并症进行调整,包括年龄、性别、种族、体重指数、糖尿病、吸烟和高血压,以确定翻修是否可预测并发症。

结果

共纳入37669例患者,其中3635例(9.6%)需要翻修手术。翻修组患者年龄更大(54.25±15.7岁对50.85±16.0岁;P<0.001);男性(59.0%对55.7%;P<0.001)和非西班牙裔白人患者比例更高(82.0%对77.4%;P<0.001)。与初次手术患者相比,翻修组的住院时间更长(1.11±2.5天对1.58±2.7天;P<0.001),伤口感染率更高(2.1%对1.4%;P=0.002),需要输血的出血事件发生率更高(1.3%对0.7%;P<0.001)。翻修组与初次手术组在脑脊液漏(0.2%对0.1%;P=0.116)、硬脊膜撕裂并发症(0.01%对0.01%;P=0.092)和神经损伤(0.008%对0.006%;P=0.691)方面的差异无统计学意义。对人口统计学和合并症进行调整后的泊松对数线性回归显示,翻修是住院时间(RR=462.95;P<0.001)、伤口感染(RR=9.22;P=0.002)和出血事件(RR=9.74;P=0.002)的显著预测因素,而它不是脑脊液漏(RR=2.61;P=0.106)、硬脊膜撕裂(RR=2.37;P=0.123)和神经损伤(RR=0.229;P=0.632)的显著预测因素。

结论

翻修手术是住院时间延长、伤口感染和需要输血的出血事件增加的显著预测因素。外科医生和患者都应该意识到,与初次椎间盘切除术相比,翻修腰椎显微椎间盘切除术后并发症风险增加。