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尼古丁贴片对牙龈和口腔健康的影响:一项叙述性综述

The Impact of Nicotine Patches on Gingival and Oral Health: A Narrative Review.

作者信息

Alayadi Haya

机构信息

Dental Health Department, College of Applied Medical Sciences, King Saud University, Riyadh, SAU.

出版信息

Cureus. 2024 Sep 30;16(9):e70571. doi: 10.7759/cureus.70571. eCollection 2024 Sep.

Abstract

Smoking significantly impacts oral health, causing periodontal disease, oral cancer, tooth discoloration, halitosis, and impaired wound healing. Nicotine replacement therapy (NRT), particularly nicotine patches, is widely used for smoking cessation. This review evaluates the literature regarding nicotine patches and their implications for oral and gum health. Nicotine patches deliver controlled nicotine doses transdermally, alleviating cravings and withdrawal symptoms. While nicotine can negatively affect oral health through vasoconstriction and reduced salivary flow, the overall impact of patches is generally positive compared to continued smoking. The primary benefit is the elimination of exposure to harmful chemicals and heat from cigarette smoke, significantly decreasing oral cancer risk and periodontal disease progression. Nicotine patches are associated with improved periodontal treatment outcomes, better wound healing, and potential anti-inflammatory effects. They may also promote improved oral hygiene practices. However, limitations include uncertain long-term effects and potential side effects like xerostomia. In conclusion, while nicotine patches may have some oral health effects, their use generally leads to significant improvements compared to continued smoking, making them valuable for promoting better oral health in individuals quitting smoking.

摘要

吸烟对口腔健康有重大影响,会导致牙周病、口腔癌、牙齿变色、口臭以及伤口愈合受损。尼古丁替代疗法(NRT),尤其是尼古丁贴片,被广泛用于戒烟。本综述评估了有关尼古丁贴片及其对口腔和牙龈健康影响的文献。尼古丁贴片通过皮肤递送可控剂量的尼古丁,减轻烟瘾和戒断症状。虽然尼古丁可通过血管收缩和唾液分泌减少对口腔健康产生负面影响,但与持续吸烟相比,贴片的总体影响通常是积极的。主要益处是消除了接触香烟烟雾中的有害化学物质和热量,显著降低口腔癌风险和牙周病进展。尼古丁贴片与改善牙周治疗效果、更好的伤口愈合以及潜在的抗炎作用相关。它们还可能促进口腔卫生习惯的改善。然而,局限性包括不确定的长期影响以及诸如口干等潜在副作用。总之,虽然尼古丁贴片可能对口腔健康有一些影响,但与持续吸烟相比其使用通常会带来显著改善,使其对于促进戒烟者的口腔健康更有益。

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本文引用的文献

1
The double-edged nature of nicotine: toxicities and therapeutic potentials.尼古丁的双重性质:毒性与治疗潜力。
Front Pharmacol. 2024 Aug 14;15:1427314. doi: 10.3389/fphar.2024.1427314. eCollection 2024.
9
Nicotine is a risk factor for dental caries: An  study.尼古丁是龋齿的一个风险因素:一项研究。
J Dent Sci. 2018 Mar;13(1):30-36. doi: 10.1016/j.jds.2017.09.006. Epub 2018 Jan 17.
10
Nicotine replacement therapy versus control for smoking cessation.尼古丁替代疗法与对照用于戒烟
Cochrane Database Syst Rev. 2018 May 31;5(5):CD000146. doi: 10.1002/14651858.CD000146.pub5.

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