Zia Emaan, Tariq Alina, Ayub Fiza, Khan Tahir Mehmood, Bukhsh Allah, Suleiman Amal K, Baig Mirza Rafi, Ahmed Shaaf, Dar Hamza Imam, Asghar Ahmad, Khalid Laiba
Institute of Pharmaceutical Sciences, University of Veterinary and Animal Sciences, Lahore, Punjab, Pakistan.
College of Clinical Pharmacy, King Faisal University, Al-Ahsa, Saudi Arabia.
J Res Pharm Pract. 2024 Sep 26;13(1):7-13. doi: 10.4103/jrpp.jrpp_15_24. eCollection 2024 Jan-Mar.
The goal of this study is to investigate the potential association between gestational anemia and antenatal depression in pregnant women.
It is a case-control study consisting of 684 pregnant women under 18 years recruited in different tertiary care hospitals, in Lahore, between June 2023 and December 2023. Utilizing an online questionnaire, data collection encompassed demographics, dietary habits, and the Edinburgh Postnatal Depression Scale (EPDS). Pregnant women with antenatal hemoglobin (Hb) levels above and below 11.0 g/dL were categorized as a nonanemic and anemic group. Statistical analysis involved Chi-square tests to explore the relationships between gestational parameters and maternal factors.
The depression scores of anemic and nonanemic pregnant women compare two groups of pregnant women based on their Hb levels: those with Hb <110 g/l during pregnancy (anemic) and those with Hb ≥110 g/l (nonanemic). The anemic group had higher depression scores than the nonanemic group, both for those with EPDS <12 points and those with EPDS ≥12 points. However, = 0.077 indicates that this difference was not statistically significant at a typical alpha level of 0.05.
No significant association was found between gestational anemia and antenatal depression in pregnant women. These findings prompt further research to unravel the intricacies of the association between gestational anemia and depression. The outcomes thus urge the researchers and health-care professionals to consider the diverse factors that may contribute to mental health outcomes during pregnancy and refine strategies for maternal care.
本研究的目的是调查孕妇妊娠期贫血与产前抑郁之间的潜在关联。
这是一项病例对照研究，于2023年6月至2023年12月在拉合尔的不同三级护理医院招募了684名18岁以下的孕妇。通过在线问卷收集数据，包括人口统计学、饮食习惯和爱丁堡产后抑郁量表（EPDS）。产前血红蛋白（Hb）水平高于和低于11.0 g/dL的孕妇分别分为非贫血组和贫血组。统计分析采用卡方检验来探讨妊娠参数与母体因素之间的关系。
根据血红蛋白水平比较两组孕妇（孕期血红蛋白<110 g/l的贫血组和血红蛋白≥110 g/l的非贫血组）贫血和非贫血孕妇的抑郁评分。贫血组的抑郁评分高于非贫血组，无论是EPDS<12分的还是EPDS≥12分的。然而，P = 0.077表明，在0.05的典型α水平下，这种差异无统计学意义。
未发现孕妇妊娠期贫血与产前抑郁之间存在显著关联。这些发现促使进一步研究以阐明妊娠期贫血与抑郁之间关联的复杂性。因此，这些结果敦促研究人员和医护人员考虑可能影响孕期心理健康结果的各种因素，并完善孕产妇护理策略。
