Massawe S N, Urassa E N, Nyström L, Lindmark G
Department of Obstetrics and Gynaecology, Muhimbili College of Health Sciences, Dar-es-Salaam, Tanzania.
Acta Obstet Gynecol Scand. 1999 Aug;78(7):573-9.
In Tanzania the prevalence of anemia in pregnancy is high inspite of a high antenatal attendance and an established national policy of routine hematinic supplementation and malaria chemosuppression to all pregnant women, free of cost in all antenatal clinics.
To assess the effectiveness of reinforcing existing antenatal clinic routines for prevention and treatment of anemia in pregnancy, combined with individual and community health education.
A prospective controlled intervention study in two antenatal clinics at primary level. At booking (median 24 weeks), 1045 women were screened for anemia and followed-up to late pregnancy (gestational age > or =34 weeks). In addition to hematinic and malaria prophylaxis, extra interventions at the study clinic included retraining of staff, group and individual counselling of women and community health education in the area.
There was a significant overall increase in median Hb from 10.1 g/dl at booking to 10.6 g/dl in late pregnancy, and prevalence of anemia (Hb < or =10.5 g/dl) was reduced from 60% at booking to 47%, at both clinics, with 57% reduction in the proportion with severe anemia (Hb <7.0 g/dl). Severely anemic women increased their median Hb by 3.2 g/dl during antenatal care. No additional effect was observed from an individual and community information program.
Ensuring an adequate supply of drugs seems to be the most important activity to achieve safe hemoglobin levels in pregnant women, but even an active antenatal program has a limited effect when anemia is highly prevalent and booking is late.
在坦桑尼亚,尽管产前检查率很高,且国家制定了向所有孕妇免费提供常规补血剂和疟疾化学预防药物的政策,所有产前诊所均可免费获取,但孕期贫血患病率仍很高。
评估强化现有产前诊所常规程序以预防和治疗孕期贫血,并结合个人及社区健康教育的有效性。
在两个基层产前诊所进行一项前瞻性对照干预研究。在预约就诊时(中位孕周24周),对1045名妇女进行贫血筛查,并随访至妊娠晚期(孕周≥34周)。除了提供补血剂和疟疾预防措施外,研究诊所的额外干预措施还包括对工作人员进行再培训、对妇女进行团体和个人咨询以及在该地区开展社区健康教育。
两个诊所的血红蛋白中位数从预约就诊时的10.1 g/dl显著增至妊娠晚期的10.6 g/dl,贫血患病率(血红蛋白≤10.5 g/dl)从预约就诊时的60%降至47%,重度贫血(血红蛋白<7.0 g/dl)比例降低了57%。重度贫血妇女在产前检查期间血红蛋白中位数增加了3.2 g/dl。未观察到个人及社区信息项目有额外效果。
确保充足的药物供应似乎是使孕妇达到安全血红蛋白水平的最重要活动,但当贫血患病率很高且预约就诊较晚时,即使积极的产前项目效果也有限。