Huang Jing-Bin, Liang Sheng-Jing, Lu Chang-Chao, Wen Zhao-Ke
Department of Cardiothoracic Surgery, The People's Hospital of Guangxi Zhuang Autonomous Region, and Guangxi Academy of Medical Sciences, 530021 Nanning, Guangxi, China.
Rev Cardiovasc Med. 2024 Sep 30;25(10):354. doi: 10.31083/j.rcm2510354. eCollection 2024 Oct.
The impact of vegetation length on therapeutic decision-making and prediction of long-term survival of patients with infective endocarditis is a highly topical issue. The aim of the study was to clarify the impact of vegetation length greater than 10 mm on long-term survival treated surgically for infective endocarditis.
Patients treated surgically for infective endocarditis in our hospital from January 2006 to November 2022 and were successfully followed up were included in the retrospective analysis.
814 survivors discharged from our medical center were successfully followed up to the date of death or the end date of the research and allocated to a group with vegetation length <10 mm (n = 432) or ≥10 mm (n = 382). The average follow-up time was 75.1 ± 1.8 months. Multivariate analysis indicated vegetation length ≥10 mm was associated with 1-year and 5-year mortality. Multivariate analysis of Cox regression identified vegetation length ≥10 mm to be associated with all-time mortality. Multivariate analysis identified male gender, long time between symptoms and surgery, more preoperative left ventricular ejection fraction (LVEF) and more preoperative aortic regurgitation to be associated with vegetation length ≥10 mm in infective endocarditis.
Our study indicated that vegetation length ≥10 mm was associated with long-term survival in patients treated surgically for infective endocarditis.
赘生物长度对感染性心内膜炎患者治疗决策及长期生存预测的影响是一个备受关注的热门问题。本研究旨在阐明赘生物长度大于10 mm对感染性心内膜炎手术治疗患者长期生存的影响。
纳入2006年1月至2022年11月在我院接受感染性心内膜炎手术治疗且随访成功的患者进行回顾性分析。
814例从我院出院的幸存者成功随访至死亡日期或研究结束日期，并分为赘生物长度<10 mm组（n = 432）和≥10 mm组（n = 382）。平均随访时间为75.1±1.8个月。多因素分析表明，赘生物长度≥10 mm与1年和5年死亡率相关。Cox回归多因素分析确定赘生物长度≥10 mm与全因死亡率相关。多因素分析确定男性、症状出现至手术时间长、术前左心室射血分数（LVEF）较高以及术前主动脉反流较多与感染性心内膜炎赘生物长度≥10 mm相关。
我们的研究表明，赘生物长度≥10 mm与感染性心内膜炎手术治疗患者的长期生存相关。
