Griggs L H, Chapman C J, McHaffie D J
Clin Genet. 1986 Jan;29(1):56-61. doi: 10.1111/j.1399-0004.1986.tb00771.x.
The inheritance of A-V conduction time in Polynesians has been examined, using ECGs taken from the population of the Tokelau Islands. As has been demonstrated in other racial groups, A-V conduction time was influenced by sex, age, and heart rate. Complex segregation analysis provides evidence for a significant polygenic influence on A-V conduction, but no evidence for a major gene. Familial correlations and commingling analysis are in agreement with this conclusion. The heritability of A-V conduction time was 0.46. The hypothesis of Møller & Heiberg (1980a) that a major gene could be influencing A-V conduction, is not supported by these data.
利用取自托克劳群岛人群的心电图，对波利尼西亚人房室传导时间的遗传情况进行了研究。正如在其他种族群体中所证实的那样，房室传导时间受性别、年龄和心率的影响。复杂分离分析为多基因对房室传导有显著影响提供了证据，但未发现主基因的证据。家族相关性和混合分析与这一结论一致。房室传导时间的遗传率为0.46。这些数据不支持Møller和Heiberg（1980a）提出的主基因可能影响房室传导的假说。
