Papageorgiou Georgios, Kasselimis Dimitrios, Angelopoulou Georgia, Tsolakopoulos Dimitrios, Laskaris Nikolaos, Tountopoulou Argyro, Korompoki Eleni, Velonakis Georgios, Chatziioannou Achilles, Spengos Konstantinos, Potagas Constantin, Vassilopoulou Sophia
Neuropsychology and Language Disorders Unit, 1st Department of Neurology, National and Kapodistrian University of Athens, Eginition Hospital, 15772 Athens, Greece;
Department of Industrial Design and Production Engineering, School of Engineering, University of West Attica, 12243 Athens, Greece;
NeuroSci. 2022 Feb 23;3(1):119-129. doi: 10.3390/neurosci3010010. eCollection 2022 Mar.
The impact of Moyamoya Disease (MMD) on cognition inadult Caucasian patients has not yet been thoroughly investigated. The current study is the first to present detailed neuropsychological data on a series of Greek patients with MMD. A group of eight patients was assessed with an extensive neuropsychological battery, including measures of episodic memory, working memory, executive functions, language, and social cognition. The results indicated that MMD may be characterized by a trichotomous neurocognitive profile, characterized by prominent impairment in working memory, executive functions, and social cognition. Overall, we stress the need for a thorough cognitive evaluation of MMD patients and further highlight the potential importance of social cognition in this particular disease. Possible associations between the three impaired cognitive domains in our group are also discussed.
烟雾病（MMD）对成年白种人患者认知功能的影响尚未得到充分研究。本研究首次呈现了一系列希腊烟雾病患者详细的神经心理学数据。一组8名患者接受了广泛的神经心理学测试，包括情景记忆、工作记忆、执行功能、语言和社会认知等方面的测量。结果表明，烟雾病可能具有三分法的神经认知特征，其特点是工作记忆、执行功能和社会认知显著受损。总体而言，我们强调对烟雾病患者进行全面认知评估的必要性，并进一步突出社会认知在这种特殊疾病中的潜在重要性。我们还讨论了本研究组中三个受损认知领域之间可能存在的关联。
