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与颈椎融合手术相比,颈椎椎板成形术的医疗成本更低:一项比较研究的系统评价和荟萃分析

Cervical Laminoplasty Is Associated With Lower Health Care Costs as Compared With Cervical Fusion Procedures: A Systematic Review and Meta-analysis of Comparative Studies.

作者信息

Baumann Anthony N, Anaspure Omkar, Patel Shiv, Kermanshahi Nazanin, Yoder R Garrett, Conry Keegan T, Preston Gordon, Hoffmann Jacob C

机构信息

School of Medicine, College of Medicine, Northeast Ohio Medical University, Rootstown, OH.

School of Medicine, College of Medicine, University of Pennsylvania, Philadelphia, PA.

出版信息

Clin Spine Surg. 2025 Jun 1;38(5):238-251. doi: 10.1097/BSD.0000000000001711. Epub 2024 Nov 1.

Abstract

STUDY DESIGN

Systematic review and meta-analysis.

OBJECTIVE

The purpose of this study is to examine the cost of CLP versus CF stratified by approach to guide decision-making.

SUMMARY OF BACKGROUND DATA

Cervical laminoplasty (CLP) and cervical fusion (CF) are viable alternatives for surgical management of cervical spine myelopathy, with no clear consensus on clinical superiority. However, despite clinical equivalence in patient outcomes, there is limited data on the relative costs between CLP and CF.

METHODS

This study searched PubMed, CINAHL, MEDLINE, and Web of Science databases. Inclusion criteria were articles that examined the cost between CLP and any type of CF (stratified by anterior, posterior, or combined approach). A random-effects continuous model for meta-analysis was performed using standardized mean difference (SMD).

RESULTS

Eleven articles were included. Patients (n = 21,033) had an average age of 56.0 ± 3.6 years and underwent either CLP (n = 4364), posterior CF (n = 3529), anterior CF (n = 13,084), or combined CF (n = 56). The mean reported cost among patients who underwent CLP (n=3742) was significantly lower compared with patients who underwent CF (n = 6329), irrespective of the approach for CF ( P = 0.028; SMD = -2.965). For subgroup analysis by surgical approach, the mean reported cost among patients treated with CLP was significantly lower as compared with patients treated with posterior CF ( P = 0.013; SMD = -1.861) and anterior CF ( P < 0.001; SMD = -0.344). Patients who underwent CLP had a significantly lower mean hardware cost than patients who underwent posterior CF ( P < 0.001; SMD = -3.275).

CONCLUSIONS

CLP appears to be associated with statistically significant and clinically relevant lower reported costs than CF, irrespective of the approach based on meta-analysis of low or moderate-quality retrospective studies. CLP may also have lower reported costs than both posterior CF and anterior CF.

LEVEL OF EVIDENCE

IV.

摘要

研究设计

系统评价与荟萃分析。

目的

本研究旨在通过手术方式分层,比较颈椎椎板成形术(CLP)与颈椎融合术(CF)的成本,以指导决策。

背景数据总结

颈椎椎板成形术(CLP)和颈椎融合术(CF)是治疗颈椎脊髓病的可行手术替代方案,在临床优势方面尚无明确共识。然而,尽管患者预后在临床上相当,但关于CLP和CF之间相对成本的数据有限。

方法

本研究检索了PubMed、CINAHL、MEDLINE和Web of Science数据库。纳入标准为研究CLP与任何类型CF(按前路、后路或联合手术方式分层)之间成本的文章。使用标准化均数差(SMD)进行随机效应连续模型的荟萃分析。

结果

纳入11篇文章。患者(n = 21,033)平均年龄为56.0 ± 3.6岁,接受了CLP(n = 4364)、后路CF(n = 3529)、前路CF(n = 13,084)或联合CF(n = 56)。接受CLP的患者(n = 3742)报告的平均成本显著低于接受CF的患者(n = 6329),无论CF的手术方式如何(P = 0.028;SMD = -2.965)。按手术方式进行亚组分析时,接受CLP治疗的患者报告的平均成本显著低于接受后路CF治疗的患者(P = 0.013;SMD = -1.861)和前路CF治疗的患者(P < 0.001;SMD = -0.344)。接受CLP的患者平均硬件成本显著低于接受后路CF的患者(P < 0.001;SMD = -3.275)。

结论

基于低质量或中等质量回顾性研究的荟萃分析,无论手术方式如何,CLP的报告成本在统计学上显著低于CF,且具有临床相关性。CLP的报告成本可能也低于后路CF和前路CF。

证据等级

IV级。

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