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儿童神经母细胞瘤的定量 MRI:超越图像定义危险因素的评估。

Quantitative MRI in Childhood Neuroblastoma: Beyond the Assessment of Image-defined Risk Factors.

机构信息

From the Department of Radiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Neurodevelopment and Cognitive Disorders, No. 136 Zhongshan Road 2, Yuzhong District, Chongqing 400014, China.

出版信息

Radiol Imaging Cancer. 2024 Nov;6(6):e240089. doi: 10.1148/rycan.240089.

Abstract

Neuroblastoma commonly occurs in children. MRI is a radiation-free imaging modality and has played an important role in identifying image-defined risk factors of neuroblastoma, providing necessary guidance for surgical resection and treatment response evaluation. However, image-defined risk factors are limited to providing structural information about neuroblastoma. With the evolution of MRI technologies, quantitative MRI can not only help assess image-defined risk factors but can also quantitatively reflect the biologic features of neuroblastoma in a noninvasive manner. Therefore, compared with anatomic imaging, these emerging quantitative MRI technologies are expected to provide more imaging biomarkers for the management of neuroblastoma. This review article discusses the current applications of quantitative MRI technologies in evaluating childhood neuroblastoma. Pediatrics, MR-Functional Imaging, Children, MRI, Neuroblastoma, Quantitative Imaging © RSNA, 2024.

摘要

神经母细胞瘤常见于儿童。磁共振成像(MRI)是一种无辐射的成像方式,在确定神经母细胞瘤的影像定义风险因素方面发挥了重要作用,为手术切除和治疗反应评估提供了必要的指导。然而,影像定义的风险因素仅限于提供神经母细胞瘤的结构信息。随着 MRI 技术的发展,定量 MRI 不仅可以帮助评估影像定义的风险因素,还可以无创地定量反映神经母细胞瘤的生物学特征。因此,与解剖成像相比,这些新兴的定量 MRI 技术有望为神经母细胞瘤的管理提供更多的影像生物标志物。本文综述了定量 MRI 技术在评估儿童神经母细胞瘤中的应用。儿科学,磁共振功能成像,儿童,磁共振成像,神经母细胞瘤,定量成像。

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本文引用的文献

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High-Risk Neuroblastoma: A Surgical Perspective.高危神经母细胞瘤:外科视角
Children (Basel). 2023 Feb 16;10(2):388. doi: 10.3390/children10020388.

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