Department of Psychology, University of Illinois at Chicago, Chicago, IL, United States.
Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, United States.
JMIR Form Res. 2024 Nov 1;8:e53744. doi: 10.2196/53744.
Approximately 4% to 8% of pregnant individuals meet the criteria for current posttraumatic stress disorder (PTSD), a known risk factor for a multitude of adverse maternal and child health outcomes. However, PTSD is rarely detected or treated in obstetric settings. Moreover, available prenatal PTSD treatments require in-person services that are often inaccessible due to barriers to care. Thus, web-based interventions offer great potential in extending PTSD treatment to high-risk pregnant individuals by providing affordable, accessible care. However, there are currently no web-based interventions designed specifically for the treatment of PTSD symptoms during pregnancy.
This study aims to develop and pilot a 6-week, web-based, cognitive behavioral therapy intervention for PTSD, SunnysideFlex, in a sample of 10 pregnant women with current probable PTSD. Consistent with established guidelines for developing and testing novel interventions, the focus of this pilot study was to evaluate the initial feasibility and acceptability of the SunnysideFlex intervention and preintervention to postintervention changes in PTSD and depression symptoms. This approach will allow for early refinement and optimization of the SunnysideFlex intervention to increase the odds of success in a larger-scale clinical trial.
The SunnysideFlex intervention adapted an existing web-based platform for postpartum depression, Sunnyside for Moms, to include revised, trauma-focused content. A total of 10 pregnant women in weeks 16 to 28 of their pregnancy who reported lifetime interpersonal trauma exposure (ie, sexual or physical assault) and with current probable PTSD (scores ≥33 per the PTSD checklist for DSM-5) were enrolled in the SunnysideFlex intervention. Assessments took place at baseline and 6 weeks (postintervention).
All participants were retained through the postintervention assessment period. Engagement was high; participants on average accessed 90% of their lessons, logged on to the platform at least weekly, and reported a generally positive user experience. Moreover, 80% (8/10) of participants demonstrated clinically meaningful reductions in PTSD symptoms from baseline to postintervention, and 50% (5/10) of participants no longer screened positive for probable PTSD at postintervention. Most (6/10, 60%) of the participants maintained subclinical depression symptoms from baseline to postintervention.
Findings from this small pilot study indicate that SunnysideFlex may be a feasible and acceptable mechanism for delivering PTSD intervention to high-risk, trauma-exposed pregnant women who might otherwise not have opportunities for services. Larger-scale trials of the intervention are necessary to better understand the impact of SunnysideFlex on PTSD symptoms during pregnancy and the postpartum period.
大约有 4%到 8%的孕妇符合当前创伤后应激障碍(PTSD)的标准,这是许多不良母婴健康结局的已知风险因素。然而,在产科环境中,PTSD 很少被发现或治疗。此外,现有的产前 PTSD 治疗需要亲自服务,但由于护理障碍,往往无法获得。因此,基于网络的干预措施为高危孕妇提供 PTSD 治疗提供了巨大的潜力,提供了负担得起的、可获得的护理。然而,目前还没有专门为治疗怀孕期间 PTSD 症状而设计的基于网络的干预措施。
本研究旨在为 10 名目前患有 PTSD 的孕妇开发和试点一项为期 6 周的基于网络的认知行为疗法 PTSD 干预措施,名为 SunnysideFlex。根据开发和测试新干预措施的既定准则,本试点研究的重点是评估 SunnysideFlex 干预措施的初步可行性和可接受性,以及 PTSD 和抑郁症状的预干预到后干预的变化。这种方法将允许早期改进和优化 SunnysideFlex 干预措施,以增加在更大规模临床试验中取得成功的机会。
SunnysideFlex 干预措施改编了现有的针对产后抑郁症的基于网络的平台 Sunnyside for Moms,以纳入修订后的、以创伤为重点的内容。共有 10 名孕妇在怀孕第 16 至 28 周,报告有终生人际创伤暴露(即性或身体虐待),且目前患有 PTSD(根据 DSM-5 的 PTSD 清单,得分≥33),参加了 SunnysideFlex 干预措施。评估在基线和 6 周(干预后)进行。
所有参与者都在干预后的评估期间保留下来。参与度很高;参与者平均访问了 90%的课程,每周至少登录一次平台,并报告了普遍积极的用户体验。此外,80%(8/10)的参与者在 PTSD 症状方面从基线到干预后表现出有临床意义的降低,50%(5/10)的参与者在干预后不再筛查出 PTSD 阳性。大多数(6/10,60%)的参与者在基线到干预后的抑郁症状仍处于亚临床水平。
这项小型试点研究的结果表明,SunnysideFlex 可能是一种为高危、创伤暴露的孕妇提供 PTSD 干预的可行且可接受的机制,否则她们可能没有机会获得服务。需要更大规模的干预试验来更好地了解 SunnysideFlex 对怀孕期间和产后 PTSD 症状的影响。