Ternby Ellen, Axelsson Ove, Ingvoldstad Malmgren Charlotta, Georgsson Susanne
Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Centre for Clinical Research Sörmland, Uppsala University, Eskilstuna, Sweden.
J Community Genet. 2024 Dec;15(6):711-721. doi: 10.1007/s12687-024-00746-3. Epub 2024 Nov 1.
Prenatal diagnosis for chromosomal anomalies is frequently used worldwide. It is important that pregnant women receive adequate counselling to make informed decisions regarding prenatal diagnosis. The aim of this study was to explore what factors influence pregnant women's decision-making process when accepting or declining prenatal screening and diagnosis. Methods: A qualitative study using inductive qualitative content analysis. Individual, semi-structured phone interviews were carried out during a five-month period in 2016-2017 with 24 pregnant women in the first trimester, living in a medium-sized Swedish city.
Two main themes emerged: (1)"Individual factors - The women's experiences, perceptions and values" with three categories "Attitude towards anomalies", "Worry and need for reassurance", "Self-perceived risk" and (2)"External factors - The women's perception of the test and others' views" with two categories "Test characteristics" and "Influence from others". Conclusions: Pregnant women's decision-making process regarding prenatal tests is multidimensional, affected by both individual factors such as experiences, perceptions and values, and external factors such as test characteristics and influence from others. Information about both test characteristics and the conditions tested is of help pregnant women in the decision-making process since it provides a better understanding of how having a child with the condition in question can affect them and their family. It is important that healthcare professionals giving information about and offering prenatal tests for chromosomal anomalies are aware of how their attitudes can influence women's decisions.
染色体异常的产前诊断在全球范围内广泛应用。孕妇接受充分的咨询以就产前诊断做出明智决策非常重要。本研究的目的是探讨哪些因素会影响孕妇在接受或拒绝产前筛查与诊断时的决策过程。方法：采用归纳性定性内容分析法进行定性研究。2016年至2017年期间，对瑞典一个中等规模城市的24名孕早期孕妇进行了为期五个月的个人半结构式电话访谈。
出现了两个主要主题：（1）“个体因素——女性的经历、认知和价值观”，包括三个类别“对异常的态度”、“担忧与寻求安心的需求”、“自我感知的风险”；（2）“外部因素——女性对检测的认知及他人的观点”，包括两个类别“检测特征”和“他人的影响”。结论：孕妇关于产前检测的决策过程是多维度的，受到个体因素如经历、认知和价值观以及外部因素如检测特征和他人影响的共同作用。关于检测特征和所检测状况的信息有助于孕妇进行决策，因为这能让她们更好地了解生育患有相关疾病的孩子会对自身及家庭产生怎样的影响。为染色体异常提供信息并进行产前检测的医护人员意识到自身态度会如何影响女性的决策非常重要。
