Department of Public Health, The University of Tennessee, Knoxville, Tennessee, United States of America.
Department of Environmental, Agricultural, and Occupational Health, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.
PLoS One. 2024 Nov 1;19(11):e0312700. doi: 10.1371/journal.pone.0312700. eCollection 2024.
Despite evidence-based recommendations for HPV vaccination, uptake among young adults is suboptimal. Limited research has explored factors that may influence HPV vaccination among young adults, as well as associated promotion and informational preferences in this group. This study aimed to examine factors associated with HPV vaccination among young adults and preferences for HPV vaccine information and promotion.
This study utilized a cross-sectional design to examine factors related to HPV vaccination among young adults on a university campus in Tennessee. Data were collected via an online survey administered to students, aged 18-26 years, from March-May 2023. Study measures included sociodemographic characteristics, health/healthcare-related factors, and perception-related measures. Data analysis included descriptive statistics and multivariable logistic regression analysis.
Out of 402 participants that completed the survey, 209 reported being vaccinated against HPV. In the adjusted model, variables associated with HPV vaccination were perceived risk (adjusted OR [aOR] = 1.12; 95% confidence interval [CI]:1.05, 1.20), perceived barriers (aOR = 0.73; 95% CI: 0.66, 0.81), higher HPV knowledge (aOR = 1.17; 95% CI: 1.03, 1.33), and receipt of healthcare provider recommendations (aOR = 12.90; 95% CI: 7.08, 23.51).
Study findings suggest that those who are vaccinated were more likely to report receiving healthcare provider recommendations, low perceived barriers, higher HPV knowledge and perceived risk. Future HPV vaccination promotion efforts for young adults may consider increasing HPV vaccine knowledge and awareness, addressing barriers, and strengthening provider recommendations.
尽管有基于证据的 HPV 疫苗接种推荐，但年轻人的接种率仍不理想。有限的研究探讨了可能影响年轻人 HPV 疫苗接种的因素，以及该人群中与 HPV 疫苗相关的推广和信息偏好。本研究旨在调查年轻人 HPV 疫苗接种的相关因素以及对 HPV 疫苗信息和推广的偏好。
本研究采用横断面设计，在田纳西州一所大学校园内调查年轻成年人 HPV 疫苗接种的相关因素。数据通过 2023 年 3 月至 5 月期间对 18-26 岁学生进行的在线调查收集。研究措施包括社会人口统计学特征、与健康/医疗保健相关的因素和感知相关的措施。数据分析包括描述性统计和多变量逻辑回归分析。
在完成调查的 402 名参与者中，有 209 人报告接种了 HPV 疫苗。在调整后的模型中，与 HPV 疫苗接种相关的变量包括感知风险（调整后的比值比 [aOR] = 1.12；95%置信区间 [CI]：1.05，1.20）、感知障碍（aOR = 0.73；95% CI：0.66，0.81）、较高的 HPV 知识（aOR = 1.17；95% CI：1.03，1.33）和获得医疗保健提供者的推荐（aOR = 12.90；95% CI：7.08，23.51）。
研究结果表明，那些接种疫苗的人更有可能报告接受了医疗保健提供者的推荐、感知障碍较低、HPV 知识较高和感知风险较高。未来针对年轻成年人的 HPV 疫苗接种推广工作可能需要提高 HPV 疫苗知识和意识，解决障碍问题，并加强提供者的推荐。
