Department of Nursing, School of Medicine, Foshan University, Foshan, China.
Foshan Women and Children's Hospital, Foshan, China.
Cancer Control. 2024 Jan-Dec;31:10732748241293989. doi: 10.1177/10732748241293989.
Vaccine hesitancy among young Chinese remains a challenge, contributing to low vaccination rates for the nonavalent Human Papillomavirus (HPV) vaccine. This study evaluated the knowledge and acceptance of this vaccine among students at a southern Chinese university and identified factors influencing these outcomes.
This cross-sectional, anonymous questionnaire survey was conducted from April to November 2023 at a multi-campus university in southern China. The questionnaire was comprised of three sections: the first collected demographic data; the second evaluated students' knowledge of the nonavalent HPV vaccine on a scale from 0 to 15, with cut-off points at 5 and 10 delineating low, medium, and high knowledge levels, respectively; the third section assessed vaccine acceptance on a scale from 8 to 40, using scores above the 50th percentile as the benchmark for positive acceptance.
Among the participants, 18% demonstrated low-level, 40.20% medium-level, and 41.70% high-level knowledge of the nonavalent HPV vaccine. Notably, 71.95% of respondents showed positive acceptance, whereas 28.05% expressed negative acceptance. Male students and those with lower economic conditions (monthly living expenses below 1000 RMB, = 0.004; 1000-1499 RMB, = 0.012) exhibited lower knowledge levels. As for acceptance, female students and those with higher monthly living expenses (1000-1499 RMB, = 0.007; 1500-1999 RMB, = 0.002; over 2000 RMB, = 0.002) demonstrated greater vaccine acceptance. A positive correlation was noted between the level of knowledge and vaccine acceptance (r = 0.256, < 0.001).
Gender and economic status are significantly associated with nonavalent HPV vaccine knowledge and acceptance among university students. These findings highlight the potential impact of targeted educational initiatives, especially for economically disadvantaged male students, in enhancing vaccine uptake rates.
中国年轻人对接种疫苗仍存在犹豫，这导致九价人乳头瘤病毒（HPV）疫苗的接种率较低。本研究评估了中国南方一所大学学生对该疫苗的认知和接受程度，并确定了影响这些结果的因素。
本横断面、匿名问卷调查于 2023 年 4 月至 11 月在中国南方的一所多校区大学进行。问卷分为三部分：第一部分收集人口统计学数据；第二部分评估学生对九价 HPV 疫苗的认知程度，分值为 0 至 15 分，5 分和 10 分分别表示低、中和高水平认知；第三部分评估疫苗接受程度，分值为 8 至 40 分，得分高于第 50 百分位数表示正向接受。
在参与者中，18%表现出对九价 HPV 疫苗的低水平认知，40.20%表现出中水平认知，41.70%表现出高水平认知。值得注意的是，71.95%的受访者表现出正向接受，而 28.05%的受访者表现出负向接受。男生和经济条件较低的学生（月生活费低于 1000 元， = 0.004；1000-1499 元， = 0.012）认知水平较低。至于接受程度，女生和月生活费较高的学生（1000-1499 元， = 0.007；1500-1999 元， = 0.002；2000 元以上， = 0.002）表现出更高的疫苗接受度。知识水平与疫苗接受度呈正相关（r = 0.256， < 0.001）。
性别和经济状况与大学生对九价 HPV 疫苗的认知和接受程度显著相关。这些发现强调了针对特定人群（特别是经济困难的男学生）开展教育计划的潜力，以提高疫苗接种率。
