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一项系统性综述,旨在研究社会经济地位对美国外周动脉疾病血管重建、颈动脉手术及主动脉瘤修复结果的影响。

A systematic review to examine the impact of socioeconomic status on revascularization for peripheral arterial disease, carotid artery surgery, and aortic aneurysm repair outcomes in the United States.

作者信息

Zil-E-Ali Ahsan, Alamarie Billal, Dogbe Leana, Tall Alpha Ahamadou, Paracha Abdul Wasay, Aziz Faisal

机构信息

Division of Vascular Surgery, Penn State Milton S. Hershey Medical Center, Hershey, PA.

Office of Medical Education, Penn State University College of Medicine, Hershey, PA.

出版信息

J Vasc Surg. 2025 Mar;81(3):777-790.e1. doi: 10.1016/j.jvs.2024.09.040. Epub 2024 Oct 31.

Abstract

OBJECTIVE

This systematic review aims to study the available literature on the impact of SES on the surgical outcomes of peripheral artery disease (PAD), carotid artery disease, and aortic aneurysms in the United States. The review also aims to report the diverse tools used to compute SES within the vascular surgery literature.

METHODS

A systematic review of English literature was conducted using the PubMed and Scopus literature databases from inception to November 2023. The review was designed on the PRISMA guidelines. It included studies reporting socioeconomic factors, income, social determinants of health, social class, and health status disparities in patients undergoing vascular surgical procedures. The risk of bias was evaluated utilizing the Risk of Bias in Non-randomized Studies - of Interventions tool. There were 1133 studies initially selected; only 19 passed the complete inclusion criteria for final assessment and reporting.

RESULTS

A total of 19 studies were examined that assessed the relationship between socioeconomic status and vascular surgery outcomes. All analyses were published between 2018 and 2023 and included a broad spectrum of patients undergoing multiple vascular procedures. A total of 10 publications addressed the role of these factors in patients with PAD, three analyzed the impact of these factors in patients with carotid artery disease, and six explored the role of these factors in patients with aortic repairs. No high risk of bias was reported for any selected study, and most studies (15/19) were based on national or large registries. The results of these studies showed widespread reporting measures of SES. The findings reported describe that lower SES is associated with a higher risk of amputation and stroke after revascularization for PAD and carotid artery surgery. Among the patients undergoing aortic repair, lower SES was more likely to present with ruptured aneurysms or symptomatic at the time of surgery.

CONCLUSIONS

Multiple metrics are used to assess SES in the vascular surgery literature. All studies associated lower SES with poorer outcomes or higher acuity of symptoms at the time of revascularization for PAD, carotid artery disease, and aortic repair. This finding highlights the need to consider SES in improving surgical outcomes and decreasing health care disparities.

摘要

目的

本系统评价旨在研究美国社会经济地位(SES)对周围动脉疾病(PAD)、颈动脉疾病和主动脉瘤手术结局影响的现有文献。该评价还旨在报告血管外科文献中用于计算SES的各种工具。

方法

使用PubMed和Scopus文献数据库对从创刊到2023年11月的英文文献进行系统评价。该评价依据PRISMA指南设计。纳入报告接受血管外科手术患者的社会经济因素、收入、健康的社会决定因素、社会阶层和健康状况差异的研究。使用非随机干预研究中的偏倚风险工具评估偏倚风险。最初筛选出1133项研究;只有19项通过完整纳入标准进行最终评估和报告。

结果

共审查了19项评估社会经济地位与血管外科手术结局之间关系的研究。所有分析均发表于2018年至2023年之间,纳入了接受多种血管手术的广泛患者群体。共有10篇出版物探讨了这些因素在PAD患者中的作用,3篇分析了这些因素对颈动脉疾病患者的影响,6篇探讨了这些因素在主动脉修复患者中的作用。所选研究均未报告高偏倚风险,且大多数研究(15/19)基于国家或大型登记处。这些研究结果显示了SES广泛的报告指标。报告的研究结果表明,较低的SES与PAD和颈动脉手术后血管再通后截肢和中风的较高风险相关。在接受主动脉修复的患者中,较低的SES更有可能在手术时出现动脉瘤破裂或有症状。

结论

血管外科文献中使用多种指标评估SES。所有研究均表明,较低的SES与PAD、颈动脉疾病和主动脉修复血管再通时较差的结局或较高的症状严重程度相关。这一发现凸显了在改善手术结局和减少医疗保健差异方面考虑SES的必要性。

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