Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, Nanjing Forestry University, Nanjing 210037, China.
Jiangsu Co-Innovation Center of Efficient Processing and Utilization of Forest Resources, International Innovation Center for Forest Chemicals and Materials, Nanjing Forestry University, Nanjing 210037, China.
Carbohydr Polym. 2025 Jan 1;347:122697. doi: 10.1016/j.carbpol.2024.122697. Epub 2024 Sep 1.
The antibiotic tetracycline (TC) significantly pollutes water bodies, adversely impacting ecosystems and human health. In this work, a bifunctional platform for simultaneous detection and removal of TC was successfully constructed by in-situ growth of Zr-MOF in BC microspheres. The in-situ growth ensured the stability, while the design of the aerogel microspheres improved the processability, convenience, and recyclability. The macropores and mesopores in the aerogel microspheres significantly improved the molecular mass transfer efficiency, and the sensitivity and selectivity of TC detection and adsorption were improved due to the size-sieving effect of the abundant micropores of Zr-MOF and the supramolecular interaction of the ligand. Owing to the hierarchical pore structure, the adsorption capacity reaches as high as 317.6 mg/g. The enrichment during the adsorption process enhances the interaction between TC and Zr-MOF, thereby significantly improving the detection sensitivity of TC. As expected, BMATH has a LOD as low as 28 ± 0.012 nM and a K as high as 1.89 ± 0.001 × 10 M, providing excellent detection performance compared to other work in recent years. The good selectivity to TC was theoretically validated through simulations with Materials Studio software (MS). It provides a novel and practical bifunctional platform for efficient fluorescence detection and adsorption of TC, which has a broad application prospect in the fields of environmental monitoring, water treatment, and food safety testing.
抗生素四环素（TC）对水体造成了严重的污染，对生态系统和人类健康产生了不利影响。在这项工作中，通过在 BC 微球中原位生长 Zr-MOF 成功构建了用于同时检测和去除 TC 的双功能平台。原位生长确保了稳定性，而气凝胶微球的设计提高了加工性、便利性和可回收性。气凝胶微球中的大孔和介孔显著提高了传质效率，并且由于 Zr-MOF 丰富的微孔的筛分效应和配体的超分子相互作用，提高了 TC 检测和吸附的灵敏度和选择性。由于分级孔结构，吸附容量高达 317.6mg/g。吸附过程中的富集增强了 TC 与 Zr-MOF 之间的相互作用，从而显著提高了 TC 的检测灵敏度。不出所料，BMATH 的检测限低至 28±0.012 nM，结合常数高达 1.89±0.001×10⁻⁶ M，与近年来的其他工作相比，具有出色的检测性能。通过 Materials Studio 软件（MS）进行模拟，从理论上验证了对 TC 的良好选择性。它为 TC 的高效荧光检测和吸附提供了一种新颖实用的双功能平台，在环境监测、水处理和食品安全检测等领域具有广阔的应用前景。
