J Hepatol. 2024 Dec;81(6):1040-1086. doi: 10.1016/j.jhep.2024.07.032. Epub 2024 Oct 31.
Liver transplantation (LT) is an established life-saving procedure. The field of LT has changed in the past 10 years from several perspectives, with the expansion of indications, transplantation of patients with acute-on-chronic liver failure, evolution of transplant oncology, the use of donations after cardiac death, new surgical techniques, and prioritisation of recipients on the waiting list. In addition, the advent of organ perfusion machines, the recognition of new forms of rejection, and the attention paid to the transition from paediatric to adult patients, have all improved the management of LT recipients. The purpose of the EASL guidelines presented here is not to cover all aspects of LT but to focus on developments since the previous EASL guidelines published in 2016.
肝移植(LT)是一种成熟的救命手术。在过去的 10 年中,LT 领域从多个方面发生了变化,包括适应证的扩大、慢加急性肝衰竭患者的移植、移植肿瘤学的发展、心脏死亡后供体的使用、新的手术技术以及等待名单上受者的优先排序。此外,器官灌注机的出现、新形式排斥反应的认识以及对从儿科到成年患者过渡的关注,都改善了 LT 受者的管理。这里介绍的 EASL 指南的目的不是涵盖 LT 的所有方面,而是侧重于自 2016 年发布的上一次 EASL 指南以来的发展。