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pH对尿液中草酸钙结晶风险的影响。

The effect of pH on the risk of calcium oxalate crystallization in urine.

作者信息

Berg C, Tiselius H G

出版信息

Eur Urol. 1986;12(1):59-61. doi: 10.1159/000472578.

DOI:10.1159/000472578
PMID:3948899
Abstract

The risk of calcium oxalate (CaOx) crystallization at different pH levels was determined in urine from recurrent CaOx-stone formers and normal subjects. The highest crystallization risk was observed between pH 4.5 and 5.5. In the pH range 6.5-7.5, there was a marked increase in crystallization of calcium phosphate (CaP). The results suggest the beneficial effect of moderate alkalinization in terms of a reduced CaOx crystallization. Reduced CaOx crystallization occurs at the expense of an increased formation of CaP crystals. Whether this increases the risk of CaP-stone formation is not known, but the CaP crystals were usually small, at least below pH 7.5.

摘要

在复发性草酸钙结石形成者和正常受试者的尿液中,测定了不同pH水平下草酸钙(CaOx)结晶的风险。在pH 4.5至5.5之间观察到最高的结晶风险。在pH 6.5 - 7.5范围内,磷酸钙(CaP)结晶明显增加。结果表明适度碱化对降低CaOx结晶具有有益作用。CaOx结晶减少是以CaP晶体形成增加为代价的。这是否会增加CaP结石形成的风险尚不清楚,但CaP晶体通常较小,至少在pH 7.5以下。

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