Griffith Centre of Biomedical and Rehabilitation Engineering (GCORE), Griffith University, Australia; School of Health Sciences and Social Work, Griffith University, Australia; Advanced Design and Prototyping Technologies (ADaPT) Institute, Griffith University, Australia.
Griffith Centre of Biomedical and Rehabilitation Engineering (GCORE), Griffith University, Australia; Department of Orthopaedic Surgery, Children's Health Queensland Hospital and Health Service, Australia.
Comput Methods Programs Biomed. 2024 Dec;257:108480. doi: 10.1016/j.cmpb.2024.108480. Epub 2024 Oct 28.
Proximal femoral osteotomy (PFO) is a frequently performed surgical procedure to correct hip deformities in the paediatric population. The optimal size of the blade plate implant in PFO is a critical but underexplored factor influencing biomechanical outcomes. This study introduces a novel approach to refine implant selection by integrating personalized neuromusculoskeletal modelling with finite element analysis. Using computed tomography scans and walking gait data from six paediatric patients with various pathologies and deformities, we assessed the impact of four distinct implant width-to-femoral neck diameter (W-D) ratios (30 %, 40 %, 50 %, and 60 %) on surgical outcomes. The results show that the risk of implant yield generally decreases with increasing W-D ratio, except for Patient P2, where the yield risk remained below 100 % across all ratios. The implant factor of safety (FoS) increased with larger W-D ratios, except for Patients P2 and P6, where the highest FoS was 2.60 (P2) and 0.49 (P6) at a 60 % W-D ratio. Bone-implant micromotion consistently remained below 40 µm at higher W-D ratios, with a 50 % W-D ratio striking the optimal balance for mechanical stability in all patients except P6. Although interfragmentary and principal femoral strains did not display consistent trends across all patients, they highlight the need for patient-specific approaches to ensure effective fracture healing. These findings highlight the importance of patient-specific considerations in implant selection, offering surgeons a more informed pathway to enhance patient outcomes and extend implant longevity. Additionally, the insights gained from this study provide valuable guidance for manufacturers in designing next-generation blade plates tailored to improve biomechanical performance in paediatric orthopaedics.
股骨近端截骨术(PFO)是一种常用于矫正儿科人群髋关节畸形的手术。在 PFO 中,刀片钢板植入物的最佳尺寸是一个关键但尚未充分探索的影响生物力学结果的因素。本研究通过将个性化神经肌肉骨骼建模与有限元分析相结合,引入了一种改进植入物选择的新方法。使用来自 6 名患有各种病理和畸形的儿科患者的计算机断层扫描扫描和步行步态数据,我们评估了四种不同植入物宽度与股骨颈直径(W-D)比(30%、40%、50%和 60%)对手术结果的影响。结果表明,除患者 P2 外,随着 W-D 比的增加,植入物屈服风险通常会降低,在所有比率下,P2 的屈服风险均低于 100%。植入物安全系数(FoS)随较大的 W-D 比增加,除患者 P2 和 P6 外,在 60%的 W-D 比时,最高的 FoS 为 2.60(P2)和 0.49(P6)。在较高的 W-D 比下,骨-植入物微运动始终保持在 40 µm 以下,除患者 P6 外,在所有患者中,50%的 W-D 比在机械稳定性方面达到了最佳平衡。虽然界面和主要股骨应变在所有患者中没有显示出一致的趋势,但它们强调了需要针对特定患者的方法来确保有效的骨折愈合。这些发现强调了在植入物选择中考虑患者个体差异的重要性,为外科医生提供了更明智的途径,以提高患者的治疗效果并延长植入物的使用寿命。此外,本研究的结果为制造商设计下一代刀片钢板提供了有价值的指导,以改善儿科骨科的生物力学性能。