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手部骨关节炎与有偿和无偿工作限制及相关社会成本的纵向关联:二级医疗保健队列中的手部骨关节炎研究

The longitudinal association of hand osteoarthritis with paid and unpaid work restrictions and related societal costs: The Hand Osteoarthritis in Secondary Care cohort.

作者信息

Terpstra Sietse E S, van de Stadt Lotte A, Boonen Annelies, Groenwold Rolf H H, Rosendaal Frits R, Kloppenburg Margreet

机构信息

Department of Rheumatology, Leiden University Medical Center, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.

Department of Rheumatology, Leiden University Medical Center, the Netherlands; Department of Rheumatology, Amsterdam Rheumatology and Immunology Centre | Reade, Amsterdam, the Netherlands.

出版信息

Osteoarthritis Cartilage. 2025 Feb;33(2):293-301. doi: 10.1016/j.joca.2024.10.013. Epub 2024 Nov 1.

Abstract

OBJECTIVES

To investigate the course of restrictions in paid and unpaid work and corresponding societal costs in patients with hand osteoarthritis (OA).

METHODS

Patients with data of at least baseline and one follow-up moment (year one up to year eight) of the Dutch Hand OSTeoArthritis in Secondary care cohort (HOSTAS) were included. The Health and Labour Questionnaire was used to assess over the last two weeks hand OA-related restrictions for paid and unpaid work. Societal costs of productivity loss were estimated with Dutch government data on 2021.

RESULTS

351 patients were included (mean age 60 years, 84% women). At baseline, 166/351 (47%) had paid work, decreasing to 54/164 (33%) at year eight. Loss of productive time over the two-week period was reported by 32/166 (19%) patients with paid work at baseline, 17/104 (16%) at year four, among whom 12/104 (11%) patients at both moments. Any restrictions over this two-week period were experienced by 89/166 patients (54%) at baseline and 41/104 (39%) at year four for those with paid work. Regarding unpaid work, 157/351 (45%) reported replacement of tasks by others at baseline and 72/164 (44%) at year eight. 205/351 (59%) reported restrictions at baseline, and 99/164 (60%) at year eight. Mean total societal costs for loss of paid and unpaid work were, per patient, €89/two weeks (95% confidence interval 52;127) at baseline and €47/two weeks (26;69) at year eight.

CONCLUSIONS

The proportion of patients with paid work decreases during follow-up, but restrictions at paid and unpaid work seem mostly stable.

摘要

目的

研究手部骨关节炎(OA)患者在有偿和无偿工作方面的受限情况及相应的社会成本。

方法

纳入荷兰二级医疗队列中手部骨关节炎(HOSTAS)至少有基线数据和一次随访数据(从第一年到第八年)的患者。使用健康与劳动问卷评估过去两周内手部OA相关的有偿和无偿工作受限情况。利用荷兰政府2021年的数据估算生产力损失的社会成本。

结果

纳入351例患者(平均年龄60岁,84%为女性)。基线时,166/351(47%)有有偿工作,到第八年降至54/164(33%)。基线时有有偿工作的患者中,32/166(19%)报告在两周期间有生产时间损失,第四年为17/104(16%),其中在两个时间点均有损失的患者为12/104(11%)。有有偿工作的患者中,基线时89/166(54%)在这两周期间有任何受限情况,第四年为41/104(39%)。关于无偿工作,基线时157/351(45%)报告他人替代了其任务,第八年为72/164(44%)。205/351(59%)在基线时报告有限制,第八年为99/164(60%)。每位患者有偿和无偿工作损失的平均总社会成本在基线时为89欧元/两周(95%置信区间52;127),第八年为47欧元/两周(26;69)。

结论

随访期间有有偿工作的患者比例下降,但有偿和无偿工作方面的受限情况似乎大多稳定。

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