Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Department of Pathology and Immunology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8118, St Louis, MO 63110, USA; Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8118, St Louis, MO 63110, USA.
Surg Pathol Clin. 2024 Dec;17(4):533-548. doi: 10.1016/j.path.2024.07.003. Epub 2024 Aug 17.
Fungal rhinosinusitis is a broad group of diseases that includes noninvasive and invasive forms with overlapping clinical presentations. While most cases of fungal rhinosinusitis follow an indolent clinical course, surgical pathologists play a crucial role in early identification of life-threating subtypes, specifically invasive fungal rhinosinusitis. This review describes fungal infections of the sinonasal tract and their histopathologic mimickers. Clinical, gross, and microscopic features that are important for diagnosis, as well as available ancillary studies, are discussed.
真菌性鼻窦炎是一组广泛的疾病,包括非侵袭性和侵袭性形式,具有重叠的临床表现。虽然大多数真菌性鼻窦炎病例呈惰性临床病程,但外科病理学家在早期识别危及生命的亚型方面发挥着至关重要的作用,特别是侵袭性真菌性鼻窦炎。本文描述了鼻窦的真菌感染及其组织病理学模拟物。讨论了对诊断很重要的临床、大体和显微镜特征以及可用的辅助研究。