Richard Marie-Edith, Provost Corentin, Delabarde Tania, Iorio Pauline, Menu Yves, Hmeydia Ghazi, Ludes Bertrand, Oppenheim Catherine, Benzakoun Joseph
Institute of Psychiatry and Neuroscience of Paris (IPNP), Université Paris Cité, INSERM U1266, 75014, Paris, France.
Service de Radiologie, GHU Paris Psychiatrie Et Neurosciences, Site Sainte-Anne, 1, Rue Cabanis, 75014, Paris, France.
Int J Legal Med. 2025 Mar;139(2):639-649. doi: 10.1007/s00414-024-03361-6. Epub 2024 Nov 4.
Due to their unique anatomy, paranasal sinuses have been used for comparative identification between post-mortem CT (PMCT) and ante-mortem CT (AMCT). However, data security issues arise when transferring raw AMCT images of a suspected identity. The aim of this study was to derive and validate an identification score based on CT slices extracted from successive CTs for the identification of subjects. For derivation procedure, we included patients who underwent two successive AMCTs at ≥ 1-year interval (n = 98), and 4 radiologists individually assessed similarity of prespecified CT slices (centered on ethmoid, frontal sinus and Left Semi-Circular Canal). Predictive values were calculated for all combinations of number of readers and slices, and the optimal compromise, termed IDScore, was selected. For validation, we included PMCTs performed between 2018 and 2022 with available comparative head AMCTs (n = 27). For each PMCT, 5 comparison procedures were performed: 1 concordant (with corresponding AMCT) and 4 discordant (with randomly selected AMCTs). Two radiologists evaluated similarity of ethmoid and frontal CT slices with a score ranging from -2 to + 2. IDScore was defined as the sum of these slice scores, averaged between the two readers. In the 135 comparison procedures, IDScore using predetermined thresholds (positive identification for IDScore > + 2, negative identification for IDScore < -1) allowed a perfect discrimination between identical subjects (Sensitivity = 100%, Specificity = 100%). IDScore could be used for remote identification of a subject with no need to access to the complete raw AMCT images, hence helping to overcome ethical and regulatory issues to access AMCT of a suspected identity.Trial registration: F20220729161623 on Health Data Hub, registered on 29 July 2022.
由于其独特的解剖结构，鼻旁窦已被用于死后CT（PMCT）和生前CT（AMCT）之间的对比识别。然而，在传输疑似身份的原始AMCT图像时会出现数据安全问题。本研究的目的是基于从连续CT中提取的CT切片得出并验证一种识别分数，用于识别受试者。在推导过程中，我们纳入了间隔≥1年接受两次连续AMCT的患者（n = 98），4名放射科医生分别评估预先指定的CT切片（以筛窦、额窦和左侧半规管为中心）的相似性。计算了所有读者数量和切片组合的预测值，并选择了最佳折衷方案，即IDScore。为了进行验证，我们纳入了2018年至2022年期间进行的PMCT以及可用的对比头部AMCT（n = 27）。对于每个PMCT，进行了5种比较程序：1种一致（与相应的AMCT）和4种不一致（与随机选择的AMCT）。两名放射科医生评估筛窦和额部CT切片的相似性，分数范围为-2至+2。IDScore定义为这些切片分数的总和，由两名读者平均得出。在135次比较程序中，使用预定阈值的IDScore（IDScore > +2为阳性识别，IDScore < -1为阴性识别）能够完美区分相同的受试者（敏感性 = 100%，特异性 = 100%）。IDScore可用于远程识别受试者，无需访问完整的原始AMCT图像，从而有助于克服获取疑似身份的AMCT时的伦理和监管问题。试验注册：健康数据中心F20220729161623，于2022年7月29日注册。
