Zhong Shaoling, Zhou Hongling, Yu Xin, Li Yue, Yang Xinhu, Zhang Jiawen, Zhou Liang, Sun Meng
The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China.
The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China; Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China.
Schizophr Res. 2024 Dec;274:374-380. doi: 10.1016/j.schres.2024.10.012. Epub 2024 Oct 28.
Violence perpetration may be linked to psychotic-like experiences (PLEs), but relevant research is limited, especially in general population. Therefore, we aimed to identify trajectories of PLEs and examine whether specific trajectories were related to violent behavior in a 3-year cohort study.
We developed a prospective cohort study and collected data in 2020 (T0), 2021 (T1), and 2022 (T2) in Guangzhou, China. A total of 3539 university students from two universities were included and completed self-report questionnaires to assess PLEs, violent ideation, violent threats, and violent acts. Socio-demographic and clinical factors were assessed and considered as confounding factors. We used growth mixture modeling to identify trajectories of PLEs. Associations between PLEs trajectories and violent behavior were examined using binary logistic regression.
At T2, 162 (5.3 %) participants had violent behavior. We identified three distinct trajectories: low stable trajectory, low increasing trajectory, and high decreasing trajectory. The binary logistic regression models revealed that the high decreasing (OR: 2.46, 95%CI:1.60-3.72) group and the low increasing (OR: 11.7, 95%CI: 7.62-17.9) were associated with higher violent risk compared to the low stable group after controlling for baseline socio-demographic and clinical factors.
Our study delineated three distinct trajectories and indicated that PLEs trajectories are related to subsequent violent ideation and violent acts. The results provide crucial clarifications regarding the nature of the associations between PLEs trajectories and violence over time.
暴力行为可能与类精神病体验(PLEs)有关,但相关研究有限,尤其是在普通人群中。因此,在一项为期3年的队列研究中,我们旨在确定PLEs的轨迹,并研究特定轨迹是否与暴力行为相关。
我们开展了一项前瞻性队列研究,并于2020年(T0)、2021年(T1)和2022年(T2)在中国广州收集数据。纳入了来自两所大学的3539名大学生,他们完成了自我报告问卷,以评估PLEs、暴力意念、暴力威胁和暴力行为。评估了社会人口统计学和临床因素,并将其视为混杂因素。我们使用生长混合模型来确定PLEs的轨迹。使用二元逻辑回归检验PLEs轨迹与暴力行为之间的关联。
在T2时,162名(5.3%)参与者有暴力行为。我们确定了三种不同的轨迹:低稳定轨迹、低上升轨迹和高下降轨迹。二元逻辑回归模型显示,在控制了基线社会人口统计学和临床因素后,与低稳定组相比,高下降组(OR:2.46,95%CI:1.60 - 3.72)和低上升组(OR:11.7,95%CI:7.62 - 17.9)与更高的暴力风险相关。
我们的研究描绘了三种不同的轨迹,并表明PLEs轨迹与随后的暴力意念和暴力行为有关。研究结果为PLEs轨迹与暴力行为随时间的关联性质提供了关键的阐释。