Department of Social Psychiatry, Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.
Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, Guangdong, China.
BMJ Open. 2024 Oct 1;14(10):e084141. doi: 10.1136/bmjopen-2024-084141.
Previous research has extensively explored the factors associated with psychotic-like experiences (PLEs). However, the characteristics and associated factors of remitted PLEs, which refer to the absence of current PLEs following previous PLEs, remain unclear. Therefore, this study aims to describe the characteristics of adolescents who reported remitted PLEs.
Cross-sectional study.
The survey was conducted from October to December 2020 in three colleges located in Guangzhou, China.
A total of 4208 college freshmen aged from 15 to 24 participated in our survey.
The 15-item positive subscale of the Community Assessment of the Psychic Experience was used to assess both lifetime and current PLEs. Multivariate logistic regression models were used to examine the associations between remitted PLEs and a range of demographic factors, lifestyle, psychosocial factors, lifetime affective symptoms and sleep problems.
Three groups of PLEs were observed: non-PLEs (47.27% of the sample), remitted PLEs (40.42%) and current PLEs (12.31%). Several factors have been identified as shared correlates of remission and absence of PLEs, including fewer recent adverse life events, greater resilience, fewer symptoms of depression and anxiety, and early waking. Furthermore, higher levels of social support (OR 1.48, 95% CI 1.01 to 2.17; OR 1.53, 95% CI 1.18 to 1.97) was a specific factor associated with the remission of PLEs. Compared with individuals without PLEs, those with remitted PLEs were more likely to be female (OR 1.50, 95% CI 1.28 to 1.75), less likely to be younger (OR 0.88, 95% CI 0.81 to 0.95) and prone to have more chronic physical illness (OR 1.67, 95% CI 1.29 to 2.16), habitual alcohol intake (OR 1.85, 95% CI 1.19 to 2.88), more childhood trauma (OR for low vs high=0.72, 95% CI 0.57 to 0.91) and the sleep problems of waking up easily (OR 1.36, 95% CI 1.12 to 1.65).
These findings suggest that remitted PLEs play a vital, unique role among three groups and provide preliminary targets for the intervention for adolescents at risk of mental health problems. Further investigation may shed light on the causality of the relationship between remitted PLEs and associated factors.
先前的研究已经广泛探讨了与精神病样体验（PLEs）相关的因素。然而，缓解型 PLEs（指在先前出现 PLEs 后当前不存在 PLEs 的情况）的特征和相关因素仍不清楚。因此，本研究旨在描述报告缓解型 PLEs 的青少年的特征。
横断面研究。
本研究于 2020 年 10 月至 12 月在中国广州的三所大学进行。
共有 4208 名 15 至 24 岁的大学新生参与了我们的调查。
使用 15 项积极分项的社区心理体验评估来评估终身和当前 PLEs。多变量逻辑回归模型用于检查缓解型 PLEs 与一系列人口统计学因素、生活方式、心理社会因素、终身情感症状和睡眠问题之间的关联。
观察到三组 PLEs：非 PLEs（样本的 47.27%）、缓解型 PLEs（40.42%）和当前 PLEs（12.31%）。一些因素已被确定为缓解和 PLEs 缺失的共同相关因素，包括近期不良生活事件较少、适应力较强、抑郁和焦虑症状较少以及早醒。此外，更高水平的社会支持（OR 1.48，95%CI 1.01 至 2.17；OR 1.53，95%CI 1.18 至 1.97）是与缓解 PLEs 相关的特定因素。与无 PLEs 的个体相比，缓解型 PLEs 的个体更可能为女性（OR 1.50，95%CI 1.28 至 1.75），不太可能为年轻人（OR 0.88，95%CI 0.81 至 0.95），并且更有可能患有慢性躯体疾病（OR 1.67，95%CI 1.29 至 2.16）、习惯性饮酒（OR 1.85，95%CI 1.19 至 2.88）、更多的儿童期创伤（OR 低 vs 高=0.72，95%CI 0.57 至 0.91）和容易醒来的睡眠问题（OR 1.36，95%CI 1.12 至 1.65）。
这些发现表明，缓解型 PLEs 在三组人群中发挥着重要的、独特的作用，并为有心理健康问题风险的青少年的干预提供了初步目标。进一步的研究可能会揭示缓解型 PLEs 与相关因素之间关系的因果关系。
