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与545名对照者相比,不育男性的36名兄弟的精子特征较低。

Lower sperm characteristics in 36 brothers of infertile men, compared with 545 controls.

作者信息

Czyglik F, Mayaux M J, Guihard-Moscato M L, David G, Schwartz D

出版信息

Fertil Steril. 1986 Feb;45(2):255-8. doi: 10.1016/s0015-0282(16)49164-8.

DOI:10.1016/s0015-0282(16)49164-8
PMID:3949026
Abstract

Among the men who volunteered to become semen donors for artificial insemination at the sperm bank of Centre d'Etude et de Conservation du Sperme Humain, Paris-Bicêtre, some were brothers of the infertile men of couples entering the Artificial Insemination with Donor program. Their sperm characteristics, compared with those of other donor candidates, are clearly lower. The difference is significant for count (78.0 versus 102.8, P less than 0.05) and very significant for the percentage of motile spermatozoa (61.5 versus 66.9, P less than 0.01) and for the percentage of normal forms (51.8 versus 62.7, P less than 0.00001). The differences are even more pronounced when the brothers of azoospermic men are considered. The possibility that some cases of infertility could have a genetic origin is discussed.

摘要

在巴黎比塞特市人类精子研究与保存中心精子库自愿成为人工授精精液捐赠者的男性中,有些是接受供精人工授精项目夫妇中不育男性的兄弟。与其他候选捐赠者相比,他们的精子特征明显更低。精子计数方面差异显著(78.0对102.8,P<0.05),活动精子百分比差异非常显著(61.5对66.9,P<0.01),正常形态百分比差异也非常显著(51.8对62.7,P<0.00001)。当考虑无精子症男性的兄弟时,差异更为明显。文中讨论了某些不育病例可能存在遗传起源的可能性。

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1
Lower sperm characteristics in 36 brothers of infertile men, compared with 545 controls.与545名对照者相比,不育男性的36名兄弟的精子特征较低。
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Semen abnormalities in artificial insemination donor candidates.人工授精供精者精液异常情况
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Correlation between semen parameters and sperm aneuploidy rates investigated by fluorescence in-situ hybridization in infertile men.荧光原位杂交技术研究不育男性精液参数与精子非整倍体率之间的相关性
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引用本文的文献

1
Case-control study of whether subfertility in men is familial.男性生育力低下是否具有家族性的病例对照研究。
BMJ. 1994 Sep 3;309(6954):570-3. doi: 10.1136/bmj.309.6954.570.