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PSMA 靶向前列腺癌成像的最新进展。

Update on PSMA-based Prostate Cancer Imaging.

机构信息

Molecular Imaging Program. National Cancer Institute, NIH, Bethesda, MD.

Molecular Imaging Program. National Cancer Institute, NIH, Bethesda, MD.

出版信息

Semin Nucl Med. 2024 Nov;54(6):941-950. doi: 10.1053/j.semnuclmed.2024.10.004. Epub 2024 Oct 28.

Abstract

The increased use of prostate-specific membrane antigen (PSMA) based PET imaging for prostate cancer (Pca) detection has revolutionized the clinical management of Pca, with higher diagnostic sensitivity for extraprostatic disease and increasing clinical utility across different stages of the disease. The integration of PSMA PET imaging into clinical guidelines and consensus documents reflects its growing importance in the personalized management of Pca. This review of recent literature highlights the rapid evolution of PSMA PET into the mainstream of staging and restaging and the decreasing reliance on conventional imaging modalities. This comprehensive review serves as a resource for clinicians and researchers involved in the domains of Pca diagnosis and management.

摘要

前列腺特异性膜抗原 (PSMA) 为基础的 PET 成像在前列腺癌 (Pca) 检测中的应用日益增多,彻底改变了 Pca 的临床管理方式,对前列腺外疾病的诊断敏感性更高,在疾病的不同阶段的临床应用也越来越广泛。PSMA PET 成像被纳入临床指南和共识文件,反映了其在 Pca 个体化管理中的重要性不断增加。本文对最新文献的回顾强调了 PSMA PET 迅速成为分期和再分期的主流,减少了对传统成像方式的依赖。这篇全面的综述为参与 Pca 诊断和管理领域的临床医生和研究人员提供了一个资源。

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1
Update on PSMA-based Prostate Cancer Imaging.PSMA 靶向前列腺癌成像的最新进展。
Semin Nucl Med. 2024 Nov;54(6):941-950. doi: 10.1053/j.semnuclmed.2024.10.004. Epub 2024 Oct 28.

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