[Genetic aspects of humoral immunity reactions to collagen in man and animals. III. An analysis of the sexual dimorphism of the levels of autoantibodies to collagen type I in systemic lupus erythematosus patients and their modifications in ontogeny].

The study of polymorphism levels of the autoantibodies to collagen type I in patients with systemic lupus erythematosus revealed the sex dimorphism of the character studied. Negative correlation of the levels of autoantibodies to collagen type I and those of sex hormones as well as modulation of the character under the action of xenobiotics were observed.