Fukasawa Y, Kano S
Fukasawa Clinic, Tochigi-pref.
Rinsho Byori. 1993 Aug;41(8):876-81.
Using enzyme-linked immunosorbent assay (ELISA), we determined the incidence of serum IgG antibodies to native type II collagen in patients with collagen diseases such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS) and overlap syndrome (OL). Raised serum IgG anti-type II collagen antibody levels were present in 11% of patients with RA, 30% with SLE, 44% with PSS and 42% with OL. There was, however, no correlation with clinical manifestations or other laboratory data.
我们采用酶联免疫吸附测定法（ELISA），测定了类风湿关节炎（RA）、系统性红斑狼疮（SLE）、进行性系统性硬化症（PSS）和重叠综合征（OL）等胶原病患者血清中抗天然II型胶原IgG抗体的发生率。RA患者中有11%、SLE患者中有30%、PSS患者中有44%以及OL患者中有42%的血清IgG抗II型胶原抗体水平升高。然而，其与临床表现或其他实验室数据并无相关性。
