León-Ibáñez Luis, Piñero David P
Clínica Oftalmológica MOAT, Castellón, Spain.
Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain.
Eur J Ophthalmol. 2025 May;35(3):930-937. doi: 10.1177/11206721241293830. Epub 2024 Nov 3.
PurposeTo evaluate the clinical outcomes of a refractive multi-segmented continuous transitional focus intraocular lens (IOL), analyzing the potential influence of patient pupil dynamics on these outcomes.MethodsRetrospective consecutive case series study enrolling 40 eyes (20 patients, 47-81 years) implanted with the Precizon Presbyopic IOL (Ophtec BV). The following clinical outcomes were analyzed during a mean follow-up of 12.1 months (2-24 months): visual acuity, refraction, contrast sensitivity (CS) under photopic and mesopic conditions, binocular defocus curve and evaluation of the perception of disturbing visual symptoms with a validated questionnaire.ResultsMean binocular uncorrected distance (UDVA), distance-corrected intermediate (DCIVA), uncorrected near (UNVA) and distance-corrected near visual acuities (DCNVA) were -0.09 ± 0.07, 0.04 ± 0.05, 0.17 ± 0.12, and 0.15 ± 0.10 logMAR, respectively. In the binocular defocus curve, mean distance-corrected visual acuity was over 0.20 logMAR for defocus levels from +1.50 to -3.00 D. No significant correlations of photopic pupil diameter with postoperative visual data were found (-0.165 ≤ r ≤ 0.192, p ≥ 0.235). Moderate correlations of mesopic pupil size were found with visual acuities for the defocus levels of -2.50 ( = 0.454, = 0.003), -3.00 ( = 0.609, < 0.001), -3.50 ( = 0.519, < 0.001), and -4.00 D ( = 0.403, = 0.010). Only significant differences were found between mesopic and photopic CS for 12 cycles/degree ( = 0.010). No cases of severe glare or halos were detected. In contrast, 10% of patients referred the severe perception of starbursts postoperatively. Full spectacle independence was referred by almost all patients (90%).ConclusionsThe IOL demonstrates effective visual restoration at various distances, characterized by high levels of visual quality and minimal dependence on pupil dynamics.
评估一种屈光性多节段连续过渡焦点人工晶状体（IOL）的临床效果，分析患者瞳孔动态变化对这些效果的潜在影响。
对40只眼（20例患者，年龄47 - 81岁）植入Precizon老视IOL（Ophtec BV）进行回顾性连续病例系列研究。在平均12.1个月（2 - 24个月）的随访期间分析以下临床结果：视力、屈光、明视和暗视条件下的对比敏感度（CS）、双眼散焦曲线以及使用经过验证的问卷评估视觉干扰症状的感知情况。
双眼平均未矫正远视力（UDVA）、远矫正中间视力（DCIVA）、未矫正近视力（UNVA）和远矫正近视力（DCNVA）分别为-0.09±0.07、0.04±0.05、0.17±0.12和0.15±0.10 logMAR。在双眼散焦曲线中，散焦水平从+1.50到-3.00 D时，平均远矫正视力超过0.20 logMAR。未发现明视瞳孔直径与术后视觉数据有显著相关性（-0.165≤r≤0.192，p≥0.235）。发现暗视瞳孔大小与散焦水平为-2.50 D（r = 0.454，p = 0.003）、-3.00 D（r = 0.609，p < 0.001）、-3.50 D（r = 0.519，p < 0.001）和-4.00 D（r = 0.403，p = 0.010）时的视力有中度相关性。仅在12周/度时发现暗视和明视CS之间存在显著差异（p = 0.010）。未检测到严重眩光或光晕病例。相比之下，10%的患者术后提到有严重的星芒感。几乎所有患者（90%）表示完全不依赖眼镜。
该IOL在不同距离均显示出有效的视力恢复，其特点是视觉质量高且对瞳孔动态变化的依赖性最小。
