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Am J Surg Pathol. 2022 Nov 1;46(11):1524-1532. doi: 10.1097/PAS.0000000000001938. Epub 2022 Aug 2.
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Optimizing palliative chemotherapy for advanced invasive mucinous adenocarcinoma of the lung.优化晚期浸润性黏液性腺癌的姑息化疗。
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Sotorasib for Lung Cancers with p.G12C Mutation.索托拉西布治疗 p.G12C 突变型肺癌。
N Engl J Med. 2021 Jun 24;384(25):2371-2381. doi: 10.1056/NEJMoa2103695. Epub 2021 Jun 4.
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Comprehensive Molecular and Clinicopathologic Analysis of 200 Pulmonary Invasive Mucinous Adenocarcinomas Identifies Distinct Characteristics of Molecular Subtypes.200 例肺部浸润性黏液性腺癌的全面分子与临床病理分析确定了分子亚型的独特特征。
Clin Cancer Res. 2021 Jul 15;27(14):4066-4076. doi: 10.1158/1078-0432.CCR-21-0423. Epub 2021 May 4.
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Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
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Ann Thorac Surg. 2021 Oct;112(4):1118-1126. doi: 10.1016/j.athoracsur.2020.09.042. Epub 2020 Nov 24.
8
Invasive mucinous adenocarcinoma of the lung: Serial CT findings, clinical features, and treatment and survival outcomes.肺浸润性黏液性腺癌:连续 CT 表现、临床特征以及治疗和生存结果。
Thorac Cancer. 2020 Dec;11(12):3463-3472. doi: 10.1111/1759-7714.13674. Epub 2020 Oct 5.
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Comparing clinicopathological features and prognosis of primary pulmonary invasive mucinous adenocarcinoma based on computed tomography findings.基于 CT 表现比较原发性肺浸润性黏液腺癌的临床病理特征和预后。
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PD-L1 Expression in Non-Small-Cell Lung Cancer Including Various Adenocarcinoma Subtypes.非小细胞肺癌包括各种腺癌亚型中的程序性死亡受体配体1(PD-L1)表达
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[侵袭性黏液腺癌的分子机制与临床治疗进展]

[Advances on Molecular Mechanism and Clinical Treatment 
in Invasive Mucinous Adenocarcinoma].

作者信息

Shi Minjun, Ye Bo

机构信息

Department of Thoratic Surgery, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 
Shanghai 200030, China.

出版信息

Zhongguo Fei Ai Za Zhi. 2024 Sep 20;27(9):685-690. doi: 10.3779/j.issn.1009-3419.2024.106.22.

DOI:10.3779/j.issn.1009-3419.2024.106.22
PMID:39492583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11534550/
Abstract

Invasive mucinous adenocarcinoma (IMA) is a special type of lung adenocarcinoma that accounts for 2% to 10% of all lung adenocarcinoma. Surgical treatment is preferred for IMA, and traditional chemotherapy drugs and targeted therapy drugs have poor efficacy in this disease. IMA has unique prognostic, imaging and molecular features. The incidence of IMA is very low, so thoracic surgeons may lack of knowledge to the disease and misdiagnose it as benign diseases such as pneumonia and tuberculosis. This article reviews and discusses the imaging, clinicopathological features, treatment methods and prognosis of IMA.
.

摘要

浸润性黏液腺癌(IMA)是肺腺癌的一种特殊类型,占所有肺腺癌的2%至10%。IMA首选手术治疗,传统化疗药物和靶向治疗药物对该疾病疗效不佳。IMA具有独特的预后、影像学和分子特征。IMA的发病率很低,因此胸外科医生可能对该疾病缺乏了解,并将其误诊为肺炎和肺结核等良性疾病。本文对IMA的影像学、临床病理特征、治疗方法及预后进行综述和讨论。