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目前预测肝切除术后肝衰竭的策略和一种新的基于超声的列线图。

Current strategies for predicting post-hepatectomy liver failure and a new ultrasound-based nomogram.

机构信息

Department of Infectious Disease, Lanzhou University First Clinical Medical College, Lanzhou 730000, Gansu Province, China.

Department of Infectious Diseases & Infectious Disease Research Laboratory, Lanzhou University First Hospital, Lanzhou 730000, Gansu Province, China.

出版信息

World J Gastroenterol. 2024 Oct 21;30(39):4254-4259. doi: 10.3748/wjg.v30.i39.4254.

Abstract

Liver cancer is associated with a few factors, such as viruses and alcohol consumption, and hepatectomy is an important treatment for patients with liver cancer. However, post-hepatectomy liver failure (PHLF) is the most serious complication and has a high mortality rate. Effective prediction of PHLF allows for the adjustment of clinical treatment strategies and is critical to the long-term prognosis of patients. Many factors have been associated with the development of PHLF, so there is an increasing interest in the development of predictive models for PHLF, such as nomograms that integrate intra-operative factors, imaging and biochemical characteristics of the patient. Ultrasound, as a simple and important examination method, plays an important role in predicting PHLF, especially the Nomogram established based on ultrasound measurements of liver stiffness and spleen area provides a more convenient way to predict the occurrence of PHLF.

摘要

肝癌与一些因素有关,如病毒和饮酒,肝切除术是肝癌患者的重要治疗方法。然而,肝切除术后肝功能衰竭(PHLF)是最严重的并发症,死亡率很高。有效的 PHLF 预测可以调整临床治疗策略,对患者的长期预后至关重要。许多因素与 PHLF 的发生有关,因此,人们越来越关注 PHLF 的预测模型的开发,例如整合术中因素、患者影像学和生化特征的列线图。超声作为一种简单而重要的检查方法,在预测 PHLF 方面发挥着重要作用,特别是基于超声测量肝脏硬度和脾脏面积建立的列线图为预测 PHLF 的发生提供了更方便的方法。

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